Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CCR1 | P32246 | 2/20 | 0.39 |
| ▸ | CCR5 | P51681 | 2/20 | 0.39 |
| ▸ | CCR8 | P51685 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.39 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1360826 | 0.98 | LMNA (0.41) | PTGS2LMNAKDM4EPOLBCCR1 | |
| SCHEMBL6512183 | 0.81 | KDM4E (0.44) | PTGS2LMNAKDM4EPOLBCCR1 | |
| SCHEMBL29049962 | 0.78 | ALDH1A1 (0.39) | PTGS2LMNAKDM4EPOLBCCR1 | |
| SCHEMBL1407984 | 0.78 | KDM4E (0.41) | PTGS2LMNAKDM4EPOLBCCR1 | |
| SCHEMBL6220452 | 0.78 | TDP1 (0.43) | PTGS2LMNAKDM4EPOLBCCR1 | |
| SCHEMBL3857735 | 0.78 | LMNA (0.41) | PTGS2LMNAKDM4EPOLBCCR1 | |
| SCHEMBL28752448 | 0.77 | KDM4E (0.42) | PTGS2LMNAKDM4EPOLBCCR1 | |
| SCHEMBL15362240 | 0.77 | TSHR (0.46) | PTGS2LMNAKDM4EPOLBCCR1 | |
| SCHEMBL23611463 | 0.76 | KDM4E (0.39) | PTGS2LMNAKDM4EPOLBCCR1 | |
| SCHEMBL3338098 | 0.76 | ALDH1A1 (0.41) | PTGS2LMNAKDM4ETDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4150232-A | NICKEL ELECTROPLATING BATH BRIGHTENER ADDITIVES | CILAG-CHEMIE A.G. (CH) | 1979-04-17 | — | — | US | disclosed |
| US-4148797-A | LEVELING AND BRIGHTENING AGENT FOR NICKEL ELECTROPLATING BATHS | CILAG-CHEMIE A.G. (CH) | 1979-04-10 | — | — | US | disclosed |
| US-4120859-A | (N-Substituted-pyridyl)-alkyl sulfonic acid betaines as electroplating additives | CILAG-CHEMIE A.G. (CH) | 1978-10-17 | — | — | US | disclosed |
| US-4067785-A | PYRIDYL ALKYL SULFONIC ACID BETAINES | CILAG-CHEMIE A.G. (CH) | 1978-01-10 | — | — | US | disclosed |