Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | CCR1 | P32246 | 2/20 | 0.44 |
| ▸ | CCR5 | P51681 | 2/20 | 0.44 |
| ▸ | CCR8 | P51685 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | METAP1 | P53582 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.44 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1407984 | 0.91 | KDM4E (0.41) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL28313514 | 0.88 | KDM4E (0.38) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL1407987 | 0.85 | LMNA (0.35) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL29211934 | 0.83 | P4HTM (0.40) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL3857735 | 0.83 | LMNA (0.41) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL1360826 | 0.83 | LMNA (0.41) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL6220452 | 0.83 | TDP1 (0.43) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL23611463 | 0.81 | KDM4E (0.39) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL11554272 | 0.81 | PTGS2 (0.40) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL2880728 | 0.79 | KDM4E (0.43) | KDM4ELMNACCR1CCR5CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107920973-B | Surface modification composition | 株式会社LG生活健康 | 2021-05-07 | — | — | CN | disclosed |
| CN-111818934-A | Dermatological product | 西姆莱斯股份公司 | 2020-10-23 | — | — | CN | disclosed |
| US-8198020-B2 | Contacting target cell or noncellular molecular entity with phagocytic marker and moiety that binds to a component that is present on or at surface of target cell or noncellular molecular entity, thereby increasing level or density of phagocytic marker on target cell; marker comprises phosphatidylserine | POTENTIA PHARMACEUTICALS, INC. (US) | 2012-06-12 | — | — | US | disclosed |
| US-20050113297-A1 | Compositions and methods for enhancing phagocytosis or phagocyte activity | POTENTIA PHARMACEUTICALS, INC. | 2005-05-26 | — | — | US | disclosed |
| WO-2005019429-A2 | COMPOSITIONS AND METHODS FOR ENHANCING PHAGOCYTOSIS OR PHAGOCYTE ACTIVITY | POTENTIA PHARMACEUTICALS, INC. (US) | 2005-03-03 | — | — | WO | disclosed |
| EP-0210227-B1 | PYRIMIDINE SULFATES FOR HAIR GROWTH | THE UPJOHN COMPANY (US) | 1990-05-02 | — | — | EP | disclosed |
| EP-0210227-A1 | PYRIMIDINE SULFATES FOR HAIR GROWTH. | UPJOHN CO (US) | 1987-02-04 | — | — | EP | disclosed |
| WO-1986004231-A1 | PYRIMIDINE SULFATES FOR HAIR GROWTH | THE UPJOHN COMPANY (US) | 1986-07-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113297-A1 | Compositions and methods for enhancing phagocytosis or phagocyte activity | CD47, ANXA11, ANXA1 | KDM4E 3736/4885LMNA 1911/4885CCR1 235/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.