Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 12/20 | 0.42 |
| ▸ | RAB9A | P51151 | 12/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | AGER | Q15109 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11559691 | 0.90 | MCL1 (0.49) | SMN1; SMN2MAPK1NPC1RAB9AHSP90AA1 | |
| SCHEMBL11564423 | 0.83 | KDR (0.49) | SMN1; SMN2NPC1RAB9AKDM4EMAPT | |
| SCHEMBL11565071 | 0.82 | ALDH1A1 (0.49) | SMN1; SMN2RAB9AKDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL11564078 | 0.80 | P2RX1 (0.48) | KDM4EL3MBTL1HTTALOX15KMT2A | |
| SCHEMBL11557569 | 0.80 | PNLIP (0.40) | SMN1; SMN2NPC1RAB9AKDM4EMAPT | |
| SCHEMBL11559729 | 0.80 | KLKB1 (0.51) | SMN1; SMN2MAPK1NPC1RAB9AALDH1A1 | |
| SCHEMBL11556748 | 0.80 | SMN1; SMN2 (0.51) | SMN1; SMN2NPC1RAB9AHSP90AA1PKM | |
| SCHEMBL11559054 | 0.80 | NR1H4 (0.50) | SMN1; SMN2NPC1RAB9AHSP90AA1KDM4E | |
| SCHEMBL11560905 | 0.79 | AVPR2 (0.39) | SMN1; SMN2NPC1RAB9AKDM4EL3MBTL1 | |
| SCHEMBL11562704 | 0.77 | P2RX1 (0.45) | HSD17B10KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4146631-A | ANTIALLERGENS, RESPIRATORY DISORDERS | MAY & BAKER LIMITED (GB) | 1979-03-27 | — | — | US | disclosed |