Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | ALPL | P05186 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 2/20 | 0.40 |
| ▸ | KLK1 | P06870 | 2/20 | 0.40 |
| ▸ | KLK6 | Q92876 | 2/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.38 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11562704 | 0.87 | P2RX1 (0.45) | HSD17B10P2RX1KMT2ATRPV1P2RX4 | |
| SCHEMBL11564423 | 0.83 | KDR (0.49) | NPC1ALPLRAB9ASMN1; SMN2PLG | |
| SCHEMBL11565071 | 0.82 | ALDH1A1 (0.49) | ALPLRAB9ASMN1; SMN2ALDH1A1ALOX15 | |
| SCHEMBL26704609 | 0.81 | NPC1 (0.61) | NPC1ALPLRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL11557569 | 0.80 | PNLIP (0.40) | NPC1ALPLRAB9ASMN1; SMN2P2RX1 | |
| SCHEMBL11564078 | 0.80 | P2RX1 (0.48) | ALPLPLGKLKB1ALOX15P2RX1 | |
| SCHEMBL11559729 | 0.80 | KLKB1 (0.51) | NPC1RAB9ASMN1; SMN2KLKB1ALDH1A1 | |
| SCHEMBL11556748 | 0.80 | SMN1; SMN2 (0.51) | NR1H4NPC1RAB9ASMN1; SMN2PLG | |
| SCHEMBL11554274 | 0.80 | SMN1; SMN2 (0.43) | NPC1ALPLRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL11560905 | 0.79 | AVPR2 (0.39) | NPC1ALPLRAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4146631-A | ANTIALLERGENS, RESPIRATORY DISORDERS | MAY & BAKER LIMITED (GB) | 1979-03-27 | — | — | US | disclosed |