Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.43 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.43 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.43 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11559725 | 0.94 | TP53 (0.44) | GUSBTP53POLBMAPTTDP1 | |
| SCHEMBL11550616 | 0.93 | GUSB (0.51) | GUSBTP53POLBMAPTTDP1 | |
| SCHEMBL11375670 | 0.91 | GUSB (0.56) | GUSBTP53POLBMAPTTDP1 | |
| SCHEMBL11556064 | 0.89 | GUSB (0.49) | GUSBTP53POLBMAPTTDP1 | |
| SCHEMBL11556538 | 0.87 | TSHR (0.47) | GUSBTP53POLBMAPTTDP1 | |
| SCHEMBL11552873 | 0.85 | PDE5A (0.44) | GUSBTP53POLBMAPTTDP1 | |
| SCHEMBL11380547 | 0.85 | MGLL (0.48) | GUSBTP53POLBMAPTTDP1 | |
| SCHEMBL11390124 | 0.84 | PDE5A (0.41) | TP53POLBMAPTTDP1KMT2A | |
| SCHEMBL11375402 | 0.84 | AMY1A (0.50) | GUSBTP53POLBMAPTTDP1 | |
| SCHEMBL11554463 | 0.84 | GUSB (0.51) | GUSBTP53POLBMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4159330-A | ANTIALLERGENS | CARLO ERBA S.P.A. (IT) | 1979-06-26 | — | — | US | disclosed |