Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | LGMN | Q99538 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25870772 | 0.87 | LGMN (0.61) | ALDH1A1KDM4ELMNASMN1; SMN2NPC1 | |
| SCHEMBL13450397 | 0.82 | ALDH1A1 (0.48) | ALDH1A1KDM4ELMNASMN1; SMN2NPC1 | |
| SCHEMBL14200387 | 0.82 | NPC1 (0.44) | ALDH1A1KDM4ELMNASMN1; SMN2NPC1 | |
| SCHEMBL22296418 | 0.82 | MAPT (0.58) | ALDH1A1KDM4ELMNASMN1; SMN2NPC1 | |
| SCHEMBL1104672 | 0.82 | SMN1; SMN2 (0.52) | ALDH1A1KDM4ELMNASMN1; SMN2NPC1 | |
| SCHEMBL23190660 | 0.81 | MAPT (0.56) | ALDH1A1KDM4ELMNASMN1; SMN2NPC1 | |
| SCHEMBL27439671 | 0.81 | NPC1 (0.46) | ALDH1A1KDM4ELMNASMN1; SMN2NPC1 | |
| SCHEMBL11555480 | 0.80 | KDM4E (0.41) | ALDH1A1KDM4ELMNAGAAL3MBTL1 | |
| SCHEMBL15703095 | 0.79 | HIF1A (0.51) | ALDH1A1KDM4ESMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL14200352 | 0.79 | MAPT (0.43) | ALDH1A1KDM4ELMNASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4133672-A | (Aminophenyl)morpholines and use thereof | UNITED STATES BORAX & CHEMICAL CORPORATION (US) | 1979-01-09 | — | — | US | claimed |
| US-4133673-A | HERBICIDES | UNITED STATES BORAX & CHEMICAL CORPORATION (US) | 1979-01-09 | — | — | US | disclosed |
| US-4133672-A | (Aminophenyl)morpholines and use thereof | UNITED STATES BORAX & CHEMICAL CORPORATION (US) | 1979-01-09 | — | — | US | disclosed |
| US-4126442-A | O-Phosphoroamidophenylmorpholine compounds and use as herbicides | UNITED STATES BORAX & CHEMICAL CORP. (US) | 1978-11-21 | — | — | US | disclosed |