SCHEMBL25870772

SCHEMBL25870772

CC(C)c1ccc(N)c(N2CCOCC2)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LGMN Q99538 4/20 0.61
MAPT P10636 6/20 0.45
GAA P10253 6/20 0.45
ALDH1A1 P00352 6/20 0.45
L3MBTL1 Q9Y468 3/20 0.45
POLB P06746 2/20 0.45
RECQL P46063 2/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
THRB P10828 1/20 0.45
BLM P54132 1/20 0.45
SMN1; SMN2 Q16637 3/20 0.45
KDM4E B2RXH2 4/20 0.44
LMNA P02545 3/20 0.44
NPC1 O15118 2/20 0.43
MAPK1 P28482 3/20 0.43
ALOX15 P16050 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
ALOX12 P18054 2/20 0.43
HTT P42858 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11554698 0.87 ALDH1A1 (0.55) LGMNMAPTGAAALDH1A1L3MBTL1
SCHEMBL25870823 0.85 GAA (0.56) LGMNMAPTGAAALDH1A1L3MBTL1
SCHEMBL25108545 0.83 GAA (0.59) LGMNMAPTGAAALDH1A1L3MBTL1
SCHEMBL14228296 0.82 LMNA (0.46) MAPTGAAALDH1A1L3MBTL1POLB
SCHEMBL14200352 0.82 MAPT (0.43) LGMNMAPTGAAALDH1A1L3MBTL1
SCHEMBL14614571 0.81 CYP3A4 (0.53) MAPTGAAALDH1A1L3MBTL1POLB
SCHEMBL25870816 0.81 ADRB1 (0.41) LGMNMAPTGAAALDH1A1L3MBTL1
SCHEMBL21968821 0.79 ALDH1A1 (0.46) MAPTGAAALDH1A1L3MBTL1POLB
SCHEMBL22296418 0.79 MAPT (0.58) MAPTGAAALDH1A1L3MBTL1POLB
SCHEMBL14200387 0.79 NPC1 (0.44) MAPTGAAALDH1A1L3MBTL1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230174470-A1 COMPOUND AS A UBR BOX DOMAIN LIGAND AUTOTAC INC. (KR) 2023-06-08 US disclosed
US-20230174470-A1 COMPOUND AS A UBR BOX DOMAIN LIGAND AUTOTAC INC. (KR) 2023-06-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230174470-A1 COMPOUND AS A UBR BOX DOMAIN LIGAND UBR4, UBQLN2, UBTF LGMN 1194/4885MAPT 235/4885GAA 996/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.