Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL496753 | 0.85 | ALDH1A1 (0.61) | MAPTGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL11764161 | 0.83 | HSD17B2 (0.49) | MAPTGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL20022733 | 0.79 | HTR1A (0.39) | MAPTGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL23598230 | 0.78 | MAPT (0.40) | MAPTGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL15195988 | 0.77 | ALDH1A1 (0.61) | MAPTGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL7568805 | 0.77 | ESR1 (0.55) | MAPTGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL31222343 | 0.77 | ALOX15 (0.70) | MAPTGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL22991116 | 0.76 | PDE7A (0.50) | MAPTGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL9643594 | 0.76 | ALDH1A1 (0.59) | MAPTGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL2861898 | 0.76 | HPGD (0.44) | MAPTGAAMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4143076-A | MERCAPTO PHENOLIC AND ALKYLTHIO PHENOLIC ANTIOXIDANTS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1979-03-06 | — | — | US | disclosed |
| US-4128530-A | Mercapto phenolic and alkylthio phenolic antioxidants | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1978-12-05 | — | — | US | disclosed |