Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 8/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.62 |
| ▸ | DRD2 | P14416 | 6/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.62 |
| ▸ | HTR1A | P08908 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.62 |
| ▸ | ADRA2B | P18089 | 5/20 | 0.62 |
| ▸ | ADRA2C | P18825 | 5/20 | 0.62 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.62 |
| ▸ | HTR2A | P28223 | 5/20 | 0.62 |
| ▸ | HTR2C | P28335 | 5/20 | 0.62 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.62 |
| ▸ | HRH1 | P35367 | 5/20 | 0.62 |
| ▸ | DRD3 | P35462 | 5/20 | 0.62 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.62 |
| ▸ | TP53 | P04637 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chloropromazine Sulfoxide SCHEMBL31540233 | 1.00 | CYP2D6 (0.62) | CYP2D6CYP1A2DRD2SLC6A4HTR1A | |
| Chloropromazine Sulfoxide SCHEMBL30463300 | 1.00 | CYP2D6 (0.62) | CYP2D6CYP1A2DRD2SLC6A4HTR1A | |
| Chloropromazine Sulfoxide SCHEMBL9724483 | 0.99 | LMNA (0.63) | CYP2D6CYP1A2DRD2SLC6A4HTR1A | |
| SCHEMBL10925157 | 0.95 | CYP2D6 (0.62) | CYP2D6CYP1A2DRD2SLC6A4HTR1A | |
| SCHEMBL11077473 | 0.83 | HTR2A (0.47) | CYP2D6CYP1A2DRD2SLC6A4HTR1A | |
| SCHEMBL9570366 | 0.82 | MEN1 (0.42) | CYP2D6CYP1A2DRD2SLC6A4HTR1A | |
| Bromide SCHEMBL8869261 | 0.81 | MEN1 (0.41) | CYP2D6CYP1A2DRD2SLC6A4HTR1A | |
| SCHEMBL9570344 | 0.81 | DRD2 (0.42) | CYP2D6CYP1A2DRD2SLC6A4HTR1A | |
| SCHEMBL18752073 | 0.81 | DRD2 (0.63) | CYP2D6CYP1A2DRD2SLC6A4HTR1A | |
| Bromide SCHEMBL8870578 | 0.80 | DRD2 (0.41) | CYP2D6CYP1A2DRD2SLC6A4HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240174700-A1 | LAYERED SUPERHYDROPHILIC TI-CU-MOFS, PREPARATION METHOD AND USE THEREOF | ZHEJIANG SHUREN UNIVERSITY (CN) | 2024-05-30 | — | — | US | claimed |
| US-11766441-B2 | Oral liquid compositions including chlorpromazine | Genus Lifesciences Inc. (US) | 2023-09-26 | — | — | US | claimed |
| WO-2023147730-A1 | LAYERED SUPER-HYDROPHILIC TI-CU-MOFS AND PREPARATION METHOD AND APPLICATION THEREOF | 浙江树人学院 | 2023-08-10 | — | — | WO | claimed |
| CN-113109474-B | Method for detecting sedative drug metabolism residues in animal tissues | 吉林省农业科学院 | 2023-08-01 | — | — | CN | claimed |
| CN-114479108-B | Layered super-hydrophilic Ti-Cu-MOFs and preparation method and application thereof | 浙江树人学院 | 2023-03-24 | — | — | CN | claimed |
| US-11426413-B2 | Oral liquid compositions including chlorpromazine | Genus Lifesciences Inc. (US) | 2022-08-30 | — | — | US | claimed |
| CN-114479108-A | Layered super-hydrophilic Ti-Cu-MOFs and preparation method and application thereof | 浙江树人学院 | 2022-05-13 | — | — | CN | claimed |
| US-20220096489-A1 | ORAL LIQUID COMPOSITIONS INCLUDING CHLORPROMAZINE | FIFTH THIRD BANK, NATIONAL ASSOCIATION | 2022-03-31 | — | — | US | claimed |
| US-20220096488-A1 | ORAL LIQUID COMPOSITIONS INCLUDING CHLORPROMAZINE | FIFTH THIRD BANK, NATIONAL ASSOCIATION | 2022-03-31 | — | — | US | claimed |
| US-11071739-B1 | Oral liquid compositions including chlorpromazine | Genus Lifesciences Inc. (US) | 2021-07-27 | — | — | US | claimed |
| CN-113109474-A | Method for detecting metabolic residues of sedative drugs in animal tissues | 吉林省农业科学院 | 2021-07-13 | — | — | CN | claimed |
| EP-0125654-B1 | PROCESS FOR THE PREPARATION OF ESPECIALLY PHARMACOLOGICALLY ACTIVE COMPOUNDS CONTAINING A SULFOXIDE GROUP | ZAMBON S.p.A. (IT) | 1987-07-29 | — | — | EP | claimed |
| US-4628087-A | Process for the preparation of pharmacologically active compounds containing a sulfoxide group | ZAMBON S.P.A. (IT) | 1986-12-09 | — | — | US | claimed |
| US-4407800-A | TRYPANOCIDES | UNIVERSITY OF VIRGINIA ALUMNI PATENTS FOUNDATION (US) | 1983-10-04 | — | — | US | claimed |
| EP-0082203-A1 | USE OF CALMODULIN BINDING DRUGS IN UTERUS TO PREVENT PREGNANCY | THE UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 1983-06-29 | — | — | EP | claimed |
| WO-1983000086-A1 | USE OF CALMODULIN BINDING DRUGS IN UTERUS TO PREVENT PREGNANCY | UNIV GEORGIA RES FOUND (US) | 1983-01-20 | — | — | WO | claimed |
| US-12583877-B2 | Layered superhydrophilic Ti—Cu-MOFs, preparation method and use thereof | ZHEJIANG SHUREN UNIVERSITY (CN) | 2026-03-24 | — | — | US | disclosed |
| US-20240174700-A1 | LAYERED SUPERHYDROPHILIC TI-CU-MOFS, PREPARATION METHOD AND USE THEREOF | ZHEJIANG SHUREN UNIVERSITY (CN) | 2024-05-30 | — | — | US | disclosed |
| WO-1983000086-A1 | USE OF CALMODULIN BINDING DRUGS IN UTERUS TO PREVENT PREGNANCY | UNIV GEORGIA RES FOUND (US) | 1983-01-20 | — | — | WO | disclosed |
| US-3976763-A | Chlorpromazine assay | HOFFMANN-LA ROCHE INC. (US) | 1976-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11426413-B2 | Oral liquid compositions including chlorpromazine | WIZ, CPNE4, CYP3A5 | CYP2D6 17/4885CYP1A2 189/4885DRD2 371/4885 |
| US-20220096488-A1 | ORAL LIQUID COMPOSITIONS INCLUDING CHLORPROMAZINE | WIZ, CPNE4, CYP3A5 | CYP2D6 17/4885CYP1A2 189/4885DRD2 371/4885 |
| US-11071739-B1 | Oral liquid compositions including chlorpromazine | WIZ, CPNE4, CYP3A5 | CYP2D6 17/4885CYP1A2 189/4885DRD2 371/4885 |
| US-11766441-B2 | Oral liquid compositions including chlorpromazine | WIZ, CPNE4, CYP3A5 | CYP2D6 17/4885CYP1A2 189/4885DRD2 371/4885 |
| US-12583877-B2 | Layered superhydrophilic Ti—Cu-MOFs, preparation method and use thereof | SLC7A1, MAOB, TH | CYP2D6 291/4885CYP1A2 124/4885DRD2 1835/4885 |
| US-20220096489-A1 | ORAL LIQUID COMPOSITIONS INCLUDING CHLORPROMAZINE | WIZ, CPNE4, CYP3A5 | CYP2D6 17/4885CYP1A2 189/4885DRD2 371/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.