SCHEMBL1155657

SCHEMBL1155657

Brc1c2ccccc2cc2cc3ccccc3cc12

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.48
HSD17B10 Q99714 4/20 0.48
HIF1A Q16665 1/20 0.48
CYP1B1 Q16678 1/20 0.48
POLB P06746 1/20 0.45
HTR2A P28223 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
CYP2A6 P11509 3/20 0.41
CYP1A2 P05177 4/20 0.40
KDM4E B2RXH2 3/20 0.40
HPGD P15428 2/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
GLA P06280 1/20 0.40
CYP2C19 P33261 1/20 0.40
GAA P10253 2/20 0.39
CYP3A4 P08684 1/20 0.39
ERBB2 P04626 1/20 0.39
FYN P06241 1/20 0.39
MAOA P21397 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL132836 0.90 POLB (0.52) ALDH1A1HSD17B10HIF1ACYP1B1POLB
SCHEMBL29527767 0.90 POLB (0.52) ALDH1A1HSD17B10HIF1ACYP1B1POLB
SCHEMBL29886729 0.87 ALDH1A1 (0.55) ALDH1A1HSD17B10HIF1ACYP1B1POLB
SCHEMBL198719 0.87 ALDH1A1 (0.55) ALDH1A1HSD17B10HIF1ACYP1B1POLB
Benzene SCHEMBL2725663 0.87 ALDH1A1 (0.50) ALDH1A1HSD17B10HIF1ACYP1B1POLB
Anthracene SCHEMBL27943251 0.85 CYP2A6 (0.48) ALDH1A1HSD17B10HIF1ACYP1B1POLB
Methyl Alcohol SCHEMBL28700048 0.83 POLB (0.52) ALDH1A1HSD17B10HIF1ACYP1B1POLB
SCHEMBL2219635 0.82 ALDH1A1 (0.48) ALDH1A1HSD17B10HIF1ACYP1B1POLB
SCHEMBL2265917 0.82 CYP2A6 (0.50) ALDH1A1HSD17B10HIF1ACYP1B1POLB
SCHEMBL27858229 0.81 ESR1 (0.47) ALDH1A1HSD17B10HIF1ACYP1B1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115583876-B Phenyl naphthacene ketone compound and preparation method and application thereof 深圳技术大学 2023-12-19 CN disclosed
US-10351580-B2 Acene-based transmitter molecules for photon upconversion THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2019-07-16 US disclosed
US-20180258111-A1 Acene-based transmitter molecules for photon upconversion THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2018-09-13 US disclosed
US-9517977-B2 Materials for electronic devices MERCK PATENT GMBH (DE) 2016-12-13 US disclosed
US-9517977-B2 Materials for electronic devices MERCK PATENT GMBH (DE) 2016-12-13 US disclosed
US-9412952-B2 Photoelectric conversion element and method of using the same, image sensor, and optical sensor FUJIFILM CORPORATION (JP) 2016-08-09 US disclosed
US-20140158859-A1 PHOTOELECTRIC CONVERSION ELEMENT AND METHOD OF USING THE SAME, IMAGE SENSOR, AND OPTICAL SENSOR FUJIFILM CORPORATION (JP) 2014-06-12 US disclosed
US-20120211701-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2012-08-23 US disclosed
US-20120211701-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2012-08-23 US disclosed
US-7892702-B2 Sensitizer dyes for photoacid generating systems FORCETEC CO., LTD. (KR) 2011-02-22 US disclosed
US-20090042105-A1 Sensitizer dyes for photoacid generating systems DCE APRILIS, INC. (US) 2009-02-12 US disclosed
US-20060019197-A1 Sensitizer dyes for photoacid generating systems APRILIS, INC. (US) 2006-01-26 US disclosed
EP-1578870-A2 SENSITIZER DYES FOR PHOTOACID GENERATING SYSTEMS Aprilis, Inc. (US) 2005-09-28 EP disclosed
WO-2004059389-A2 SENSITIZER DYES FOR PHOTOACID GENERATING SYSTEMS APRILIS, INC. (US) 2004-07-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180258111-A1 Acene-based transmitter molecules for photon upconversion ACE, ACE2, AGTR1 ALDH1A1 93/4885HSD17B10 3607/4885HIF1A 2517/4885
US-10351580-B2 Acene-based transmitter molecules for photon upconversion ACE, ACE2, AGTR1 ALDH1A1 93/4885HSD17B10 3607/4885HIF1A 2517/4885
US-20090042105-A1 Sensitizer dyes for photoacid generating systems HRH2, ALAD, HRH1 ALDH1A1 183/4885HSD17B10 489/4885HIF1A 2172/4885
US-20120211701-A1 MATERIALS FOR ELECTRONIC DEVICES XPOT, ETV6, ERCC1 ALDH1A1 106/4885HSD17B10 3009/4885HIF1A 4048/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.