SCHEMBL7863398

SCHEMBL7863398

FC(F)(F)c1ccc(Br)c(Br)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN5 P54829 1/20 0.41
TAS2R14 Q9NYV8 1/20 0.41
MAPT P10636 1/20 0.40
XBP1 P17861 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
TSHR P16473 2/20 0.39
MAPK1 P28482 1/20 0.39
CES2 O00748 2/20 0.39
ALDH1A1 P00352 2/20 0.38
KIF11 P52732 2/20 0.37
NOS3 P29474 1/20 0.37
NOS2 P35228 1/20 0.37
EPHX2 P34913 1/20 0.37
PKM P14618 1/20 0.36
BACE1 P56817 1/20 0.36
GPR3 P46089 1/20 0.36
PTPN1 P18031 1/20 0.36
PTPN6 P29350 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29637726 1.00 PTPN5 (0.41) PTPN5TAS2R14MAPTXBP1NPSR1
SCHEMBL29380184 0.80 PDE2A (0.42) PTPN5TAS2R14MAPTXBP1NPSR1
SCHEMBL29453079 0.80 PDE2A (0.46) PTPN5TAS2R14MAPTXBP1NPSR1
SCHEMBL624000 0.80 PDE2A (0.42) PTPN5TAS2R14MAPTXBP1NPSR1
SCHEMBL607667 0.80 PDE2A (0.46) PTPN5TAS2R14MAPTXBP1NPSR1
SCHEMBL29632676 0.80 MAPT (0.53) PTPN5TAS2R14MAPTXBP1NPSR1
SCHEMBL496276 0.80 MAPT (0.53) PTPN5TAS2R14MAPTXBP1NPSR1
SCHEMBL17158464 0.80 TAS2R14 (0.39) PTPN5TAS2R14MAPTXBP1NPSR1
SCHEMBL29454603 0.80 CES2 (0.50) PTPN5TAS2R14MAPTXBP1NPSR1
SCHEMBL29762963 0.80 IDO1 (0.44) PTPN5TAS2R14MEN1KMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114213441-B Boron or phosphorus fused ring compound, preparation method thereof and light-emitting device 中国科学院长春应用化学研究所 2023-12-01 CN disclosed
CN-116813475-A Halogenated synthesis method of aromatic ring compound 北京大学 2023-09-29 CN disclosed
CN-114213441-A Boron-doped or phosphorus-doped fused ring compound, preparation method thereof and light-emitting device 中国科学院长春应用化学研究所 2022-03-22 CN disclosed
EP-0956312-B1 PROCESS FOR PRODUCING PHENYLENE-CONTAINING POLYMER AND FILM-FORMING MATERIAL JSR CORP (JP) 2001-10-10 EP disclosed
US-6300465-B1 Process for producing phenylene-containing polymer and film-forming material JSR CORPORATION (JP) 2001-10-09 US disclosed