Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL115575 | 0.93 | LMNA (0.39) | LMNACYP3A4TDP1MIFTP53 | |
| SCHEMBL15295495 | 0.91 | LMNA (0.38) | LMNACYP3A4TDP1MIFTP53 | |
| Hydrochloric Acid SCHEMBL6058391 | 0.91 | LMNA (0.38) | LMNACYP3A4TDP1MIFTP53 | |
| SCHEMBL14693766 | 0.91 | LMNA (0.38) | LMNACYP3A4TDP1MIFTP53 | |
| SCHEMBL4738364 | 0.91 | LMNA (0.38) | LMNACYP3A4TDP1MIFTP53 | |
| SCHEMBL1206687 | 0.89 | LMNA (0.34) | LMNACYP3A4TDP1MIFTP53 | |
| SCHEMBL561783 | 0.89 | LMNA (0.34) | LMNACYP3A4TDP1MIFTP53 | |
| Hydrochloric Acid SCHEMBL1404111 | 0.89 | LMNA (0.37) | LMNACYP3A4TDP1MIFTP53 | |
| Hydrochloric Acid SCHEMBL1404110 | 0.89 | LMNA (0.37) | LMNACYP3A4TDP1MIFTP53 | |
| Hydrochloric Acid SCHEMBL1898174 | 0.89 | LMNA (0.37) | LMNACYP3A4TDP1MIFTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0752629-B1 | Fixing member and fixing apparatus including same | CANON KK (JP) | 2003-08-27 | — | — | EP | disclosed |
| US-5863660-A | SURFACE LAYER COMPRISING A SILICONE RUBBER LAYER CONTAINING A METAL COMPOUND SELECTED FROM THE GROUP CONSISTING OF ALUMINUM NITRATE, FERROUS SULFATE, FERRIC CHLORIDE AND ALUMINUM CHLORIDE; ELECTROGRAPHY ROLLER | CANON KABUSHIKI KAISHA (JP) | 1999-01-26 | — | — | US | disclosed |
| EP-0752629-A1 | Fixing member and fixing apparatus including same | CANON KABUSHIKI KAISHA (JP) | 1997-01-08 | — | — | EP | disclosed |