Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 2/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.31 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1898174 | 0.95 | LMNA (0.37) | LMNACYP3A4TDP1KDM4EGAA | |
| SCHEMBL115575 | 0.95 | LMNA (0.39) | LMNACYP3A4TDP1KDM4EGAA | |
| SCHEMBL4738364 | 0.93 | LMNA (0.38) | LMNACYP3A4TDP1KDM4EGAA | |
| SCHEMBL15295495 | 0.93 | LMNA (0.38) | LMNACYP3A4TDP1KDM4EGAA | |
| SCHEMBL14693766 | 0.93 | LMNA (0.38) | LMNACYP3A4TDP1KDM4EGAA | |
| Hydrochloric Acid SCHEMBL6058391 | 0.93 | LMNA (0.38) | LMNACYP3A4TDP1KDM4EGAA | |
| Bromide SCHEMBL5527408 | 0.91 | LMNA (0.37) | LMNACYP3A4TDP1KDM4EGAA | |
| Hydrochloric Acid SCHEMBL1898172 | 0.91 | LMNA (0.37) | LMNACYP3A4TDP1KDM4EGAA | |
| Hydrochloric Acid SCHEMBL1404110 | 0.91 | LMNA (0.37) | LMNACYP3A4TDP1KDM4EGAA | |
| SCHEMBL7097256 | 0.89 | LMNA (0.35) | LMNACYP3A4TDP1MIFTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119053608-A | Novel compound, conjugated polymer, method for producing same, composition for film formation, organic thin film, and organic semiconductor element | 东曹株式会社 | 2024-11-29 | — | — | CN | disclosed |
| WO-2024135401-A1 | INK COMPOSITION FOR PRODUCTION OF PHOTOELECTRIC CONVERSION ELEMENTS, METHOD FOR PRODUCING INK COMPOSITION FOR PRODUCTION OF PHOTOELECTRIC CONVERSION ELEMENTS, HIGH-MOLECULAR-WEIGHT COMPOUND, AND METHOD FOR PRODUCING HIGH-MOLECULAR-WEIGHT COMPOUND | 住友化学株式会社 | 2024-06-27 | — | — | WO | disclosed |
| WO-2024135402-A1 | INK COMPOSITION FOR PRODUCING PHOTOELECTRIC CONVERSION ELEMENTS, METHOD FOR PRODUCING INK COMPOSITION FOR PRODUCING PHOTOELECTRIC CONVERSION ELEMENTS, POLYMER COMPOUND AND METHOD FOR PRODUCING POLYMER COMPOUND | 住友化学株式会社 | 2024-06-27 | — | — | WO | disclosed |
| US-20210139643-A1 | POLYMER COMPOUND AND ORGANIC PHOTOELECTRIC CONVERSION ELEMENT USING SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2021-05-13 | — | — | US | disclosed |
| US-9412950-B2 | Polymer compound and organic photoelectric conversion device | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-08-09 | — | — | US | disclosed |
| EP-2291427-B1 | SULFONATED POLYTHIOPHENES COMPRISING FUSED RING REPEAT UNITS | SOLVAY USA INC (US) | 2016-03-30 | — | — | EP | disclosed |
| US-20140373912-A1 | POLYMER COMPOUND AND ORGANIC PHOTOELECTRIC CONVERSION DEVICE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-12-25 | — | — | US | disclosed |
| US-8906520-B2 | Sulfonated polythiophenes comprising fused ring repeat units | SOLVAY USA, INC. (US) | 2014-12-09 | — | — | US | disclosed |
| US-20130200351-A1 | POLYMER COMPOUND AND ORGANIC PHOTOELECTRIC CONVERSION DEVICE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-08-08 | — | — | US | disclosed |
| US-8476474-B2 | Asymmetric styryl derivatives and organic light emitting diode prepared using the same | DOOSAN CORPORATION (KR) | 2013-07-02 | — | — | US | disclosed |
| WO-2006077412-A1 | THIENOPYRROLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2006-07-27 | — | — | WO | disclosed |
| US-20060122195-A1 | Sulphonamide compounds that modulate chemokine receptor activity (ccr4) | ASTRAZENECA AB (SE) | 2006-06-08 | — | — | US | disclosed |
| EP-0752629-B1 | Fixing member and fixing apparatus including same | CANON KK (JP) | 2003-08-27 | — | — | EP | disclosed |
| US-6335447-B1 | BACTERICIDES | TOYAMA CHEMICAL CO., LTD. (JP) | 2002-01-01 | — | — | US | disclosed |
| EP-1070713-A1 | QUINOLONECARBOXYLIC ACID DERIVATIVES OR SALTS THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2001-01-24 | — | — | EP | disclosed |
| US-5863660-A | SURFACE LAYER COMPRISING A SILICONE RUBBER LAYER CONTAINING A METAL COMPOUND SELECTED FROM THE GROUP CONSISTING OF ALUMINUM NITRATE, FERROUS SULFATE, FERRIC CHLORIDE AND ALUMINUM CHLORIDE; ELECTROGRAPHY ROLLER | CANON KABUSHIKI KAISHA (JP) | 1999-01-26 | — | — | US | disclosed |
| EP-0752629-A1 | Fixing member and fixing apparatus including same | CANON KABUSHIKI KAISHA (JP) | 1997-01-08 | — | — | EP | disclosed |
| EP-0074008-B1 | PROCESS FOR PRODUCING ALPHA-ARYLALKANOIC ACID ESTERS | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1984-10-10 | — | — | EP | disclosed |
| US-4433160-A | Process for producing α-arylalkanoic acid ester | TAISHO PHARMACEUTICAL COMPANY, LTD. (JP) | 1984-02-21 | — | — | US | disclosed |
| EP-0074008-A2 | Process for producing alpha-arylalkanoic acid esters | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1983-03-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060122195-A1 | Sulphonamide compounds that modulate chemokine receptor activity (ccr4) | CCR4, CCR1, CCR3 | LMNA 4864/4885CYP3A4 242/4885TDP1 4583/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.