Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | CRHBP | P24387 | 1/20 | 0.54 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | KIF20A | O95235 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11557633 | 1.00 | ALDH1A1 (0.56) | ALDH1A1HSD17B10TDP1CRHBPCRHR2 | |
| SCHEMBL3369590 | 0.81 | CRHBP (0.56) | ALDH1A1HSD17B10TDP1CRHBPCRHR2 | |
| SCHEMBL5040968 | 0.78 | CRHBP (0.67) | ALDH1A1CRHBPCRHR2KDM4EMAPT | |
| SCHEMBL5040966 | 0.78 | CRHBP (0.67) | ALDH1A1CRHBPCRHR2KDM4EMAPT | |
| SCHEMBL13485331 | 0.77 | KIF20A (0.60) | ALDH1A1HSD17B10TDP1CRHBPCRHR2 | |
| SCHEMBL5717693 | 0.77 | CRHBP (0.65) | ALDH1A1HSD17B10TDP1CRHBPCRHR2 | |
| SCHEMBL5717695 | 0.77 | CRHBP (0.65) | ALDH1A1HSD17B10TDP1CRHBPCRHR2 | |
| SCHEMBL2524856 | 0.76 | ALDH1A1 (0.61) | ALDH1A1HSD17B10TDP1CRHBPCRHR2 | |
| SCHEMBL1254172 | 0.76 | ALDH1A1 (0.61) | ALDH1A1HSD17B10TDP1CRHBPCRHR2 | |
| SCHEMBL8544542 | 0.74 | CRHBP (0.49) | ALDH1A1HSD17B10TDP1CRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4172090-A | FROM ISOAZOLE AND BENZALDEHYDE | BASF AKTIENGESELLSCHAFT (DE) | 1979-10-23 | — | — | US | disclosed |