Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.73 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL991850 | 1.00 | MEN1 (0.73) | MEN1KMT2ATDP1HTTNPC1 | |
| SCHEMBL18013744 | 0.88 | TDP1 (0.73) | MEN1KMT2ATDP1NPC1RAB9A | |
| SCHEMBL11558044 | 0.87 | MEN1 (0.71) | MEN1KMT2ATDP1NPC1RAB9A | |
| SCHEMBL11554831 | 0.87 | MEN1 (0.71) | MEN1KMT2ATDP1NPC1RAB9A | |
| SCHEMBL10668802 | 0.86 | MEN1 (0.79) | MEN1KMT2ATDP1ALDH1A1TSHR | |
| SCHEMBL10667435 | 0.86 | MEN1 (0.79) | MEN1KMT2ATDP1ALDH1A1TSHR | |
| SCHEMBL11561346 | 0.84 | MEN1 (1.00) | MEN1KMT2ATDP1TSHRTP53 | |
| SCHEMBL10422505 | 0.84 | MEN1 (0.77) | MEN1KMT2ATDP1ALDH1A1TSHR | |
| SCHEMBL9060429 | 0.84 | MEN1 (1.00) | MEN1KMT2ATDP1TSHRTP53 | |
| SCHEMBL992112 | 0.84 | MEN1 (1.00) | MEN1KMT2ATDP1TSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4146623-A | SUBSTITUTED FUROIC ACIDS AND ESTERS | RICHARDSON-MERRELL INC. (US) | 1979-03-27 | — | — | US | disclosed |
| US-4110351-A | Hypolipidemic agents RO- or RS- substituted furoic acids, esters and salts | RICHARDSON-MERRELL INC. (US) | 1978-08-29 | — | — | US | disclosed |