Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | PLA2G4B | P0C869 | 8/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19821665 | 0.88 | MEN1 (0.66) | MEN1KMT2ATDP1PLA2G4BTSHR | |
| SCHEMBL18013744 | 0.88 | TDP1 (0.73) | MEN1KMT2ATDP1TSHRALDH1A1 | |
| SCHEMBL11558044 | 0.86 | MEN1 (0.71) | MEN1KMT2ATDP1PLA2G4BTSHR | |
| SCHEMBL11554831 | 0.86 | MEN1 (0.71) | MEN1KMT2ATDP1PLA2G4BTSHR | |
| SCHEMBL992355 | 0.83 | MEN1 (0.66) | MEN1KMT2ATDP1TSHRALDH1A1 | |
| SCHEMBL991809 | 0.83 | MEN1 (0.66) | MEN1KMT2ATDP1TSHRALDH1A1 | |
| SCHEMBL18256284 | 0.83 | MEN1 (0.66) | MEN1KMT2ATDP1TSHRALDH1A1 | |
| SCHEMBL991850 | 0.82 | MEN1 (0.73) | MEN1KMT2ATDP1PLA2G4BTSHR | |
| SCHEMBL11563597 | 0.82 | MEN1 (0.73) | MEN1KMT2ATDP1PLA2G4BTSHR | |
| SCHEMBL10422665 | 0.82 | MEN1 (0.77) | MEN1KMT2ATDP1PLA2G4BTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180028487-A1 | DERMATOLOGICAL FORMULATIONS OF 2-(2-ETHOXY-2-OXOETHYL)(METHYL)AMINO-2-OXOETHYL 5-(TETRADECYLOXY)FURAN-2-CARBOXYLATE | DERMIRA, INC. | 2018-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180028487-A1 | DERMATOLOGICAL FORMULATIONS OF 2-(2-ETHOXY-2-OXOETHYL)(METHYL)AMINO-2-OXOETHYL 5-(TETRADECYLOXY)FURAN-2-CARBOXYLATE | CUTA, CYP1A2, DPM1 | MEN1 3030/4885KMT2A 339/4885TDP1 2071/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.