Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.41 |
| ▸ | CHRNG | P07510 | 1/20 | 0.41 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.41 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10921538 | 0.83 | ALDH1A1 (0.46) | PARP1SMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL11559836 | 0.79 | SMN1; SMN2 (0.49) | PARP1SMN1; SMN2MEN1KMT2ARAB9A | |
| SCHEMBL14756573 | 0.79 | ALDH1A1 (0.50) | PARP1SMN1; SMN2ALDH1A1RAB9ANPC1 | |
| SCHEMBL641112 | 0.79 | PARP1 (0.48) | PARP1SMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL2952721 | 0.77 | PARP1 (0.52) | PARP1SMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL12332580 | 0.76 | LMNA (0.45) | ALDH1A1RAB9ANPC1KDM4ETSHR | |
| SCHEMBL9558937 | 0.76 | F2 (0.42) | SMN1; SMN2MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL9874864 | 0.74 | NPC1 (0.57) | SMN1; SMN2MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL13478834 | 0.74 | PARP1 (0.52) | PARP1SMN1; SMN2MEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL11553880 | 0.74 | BLM (0.44) | SMN1; SMN2MEN1KMT2AALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4151169-A | DECYCLIZATION, CYCLIZATION | GRUPPO LEPETIT (IT) | 1979-04-24 | — | — | US | disclosed |
| US-4119635-A | SEDATIVES, HYPNOTICS, TRANQUILIZERS | GRUPPO LEPETIT S.P.A. (IT) | 1978-10-10 | — | — | US | disclosed |