Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | IGF1R | P08069 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1155842 | 0.94 | TLR8 (0.36) | TLR8MCHR1IGF1R | |
| SCHEMBL2784756 | 0.89 | — | — | |
| SCHEMBL4546505 | 0.82 | TLR8 (0.36) | TLR8MCHR1PDE4APDE4BPDE4C | |
| SCHEMBL12595641 | 0.82 | TLR8 (0.36) | TLR8MCHR1PDE4APDE4BPDE4C | |
| SCHEMBL680229 | 0.81 | TLR8 (0.36) | TLR8MCHR1PDE4APDE4BPDE4C | |
| SCHEMBL6923222 | 0.81 | TLR8 (0.36) | TLR8MCHR1PDE4APDE4BPDE4C | |
| SCHEMBL13198868 | 0.81 | TLR8 (0.36) | TLR8MCHR1PDE4APDE4BPDE4C | |
| SCHEMBL6825504 | 0.80 | TLR8 (0.43) | TLR8MCHR1PDE4APDE4BPDE4C | |
| SCHEMBL6131641 | 0.80 | GPR88 (0.32) | — | |
| SCHEMBL2764804 | 0.80 | TLR8 (0.40) | TLR8MCHR1PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7638594-B2 | Conjugated polymers containing spirobifluorene units and the use thereof | MERCK PATENT GMBH (DE) | 2009-12-29 | — | — | US | disclosed |
| US-7323533-B2 | Conjugated polymers containing spirobifluorene units and the use thereof | COVION ORGANIC SEMICONDUCTORS GMBH (DE) | 2008-01-29 | — | — | US | disclosed |
| US-20070265473-A1 | CONJUGATED POLYMERS CONTAINING SPIROBIFLUORENE UNITS AND THE USE THEREOF | COVION ORGANIC SEMICONDUCTORS GMBH (DE) | 2007-11-15 | — | — | US | disclosed |
| US-7288617-B2 | Conjugated polymers containing spirobifluorene units and fluorene units, and the use thereof | MERCK PATENT GMBH (DE) | 2007-10-30 | — | — | US | disclosed |
| US-20050038223-A1 | Conjugated polymers containing spirobifluorene units and the use thereof | MERCK PATENT GMBH (DE) | 2005-02-17 | — | — | US | disclosed |
| US-20040135131-A1 | Conjugated polymers containing spirobifluorene units and fluorene units, and the use thereof | MERCK PATENT GMBH (DE) | 2004-07-15 | — | — | US | disclosed |
| EP-1427768-A2 | CONJUGATED POLYMERS CONTAINING SPIROBIFLUORENE UNITS AND THE USE THEREOF | Covion Organic Semiconductors GmbH (DE) | 2004-06-16 | — | — | EP | disclosed |
| WO-2003020790-A2 | CONJUGATED POLYMERS CONTAINING SPIROBIFLUORENE UNITS AND THE USE THEREOF | COVION ORGANIC SEMICONDUCTORS GMBH (DE) | 2003-03-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070265473-A1 | CONJUGATED POLYMERS CONTAINING SPIROBIFLUORENE UNITS AND THE USE THEREOF | ALDH1A2, SELE, PPOX | TLR8 996/4885MCHR1 2958/4885PDE4A 4402/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.