Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.45 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.45 |
| ▸ | ACHE | P22303 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11095874 | 0.93 | OPRM1 (0.44) | OPRM1OPRL1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL11075750 | 0.90 | OPRM1 (0.46) | OPRM1OPRL1ACHEKMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11099770 | 0.89 | OPRM1 (0.45) | OPRM1OPRL1ACHEKMT2ASMN1; SMN2 | |
| SCHEMBL11093742 | 0.88 | ACHE (0.46) | OPRM1OPRL1ACHEKMT2ASMN1; SMN2 | |
| SCHEMBL11097716 | 0.87 | OPRM1 (0.43) | OPRM1OPRL1ACHESMN1; SMN2THRB | |
| SCHEMBL11081467 | 0.85 | OPRM1 (0.50) | OPRM1OPRL1KMT2AMEN1ALOX5 | |
| SCHEMBL11095875 | 0.84 | OPRM1 (0.49) | OPRM1OPRL1THRBTHRAALOX5 | |
| SCHEMBL11077394 | 0.84 | OPRM1 (0.45) | OPRM1OPRL1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL11558462 | 0.84 | OPRM1 (0.48) | OPRM1OPRL1KMT2ATHRBTHRA | |
| SCHEMBL11088920 | 0.84 | CYP3A4 (0.39) | OPRM1OPRL1ACHEKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4180584-A | ANALGESIC; NARCOTIC ANTAGONIST | THE UPJOHN COMPANY (US) | 1979-12-25 | — | — | US | disclosed |
| US-4065573-A | ANALGESICS | THE UPJOHN COMPANY (US) | 1977-12-27 | — | — | US | disclosed |