Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.48 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.48 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11095875 | 0.97 | OPRM1 (0.49) | OPRM1OPRL1GRIN1GRIN2AGRIN2B | |
| SCHEMBL11081467 | 0.88 | OPRM1 (0.50) | OPRM1OPRL1ALOX5KMT2ASLC6A2 | |
| SCHEMBL11093745 | 0.88 | ALOX5 (0.44) | OPRM1OPRL1GRIN1GRIN2AGRIN2B | |
| SCHEMBL11069457 | 0.87 | OPRM1 (0.50) | OPRM1OPRL1ALOX5KMT2A | |
| SCHEMBL11096411 | 0.87 | GRIN1 (0.50) | OPRM1OPRL1GRIN1GRIN2AGRIN2B | |
| Ethylene SCHEMBL11550591 | 0.85 | OPRM1 (0.48) | OPRM1OPRL1ALOX5KMT2A | |
| SCHEMBL11075750 | 0.84 | OPRM1 (0.46) | OPRM1OPRL1ALOX5KMT2A | |
| SCHEMBL11558458 | 0.84 | OPRM1 (0.45) | OPRM1OPRL1ALOX5THRATHRB | |
| Hydrochloric Acid SCHEMBL11099770 | 0.84 | OPRM1 (0.45) | OPRM1OPRL1ALOX5KMT2A | |
| SCHEMBL11095874 | 0.83 | OPRM1 (0.44) | OPRM1OPRL1ALOX5THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4180584-A | ANALGESIC; NARCOTIC ANTAGONIST | THE UPJOHN COMPANY (US) | 1979-12-25 | — | — | US | disclosed |
| US-4065573-A | ANALGESICS | THE UPJOHN COMPANY (US) | 1977-12-27 | — | — | US | disclosed |