Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2927939 | 0.75 | — | — | |
| SCHEMBL2928489 | 0.72 | TSHR (0.40) | TSHRTDP1ALDH1A1 | |
| SCHEMBL13294358 | 0.72 | TSHR (0.40) | TSHRTDP1ALDH1A1 | |
| SCHEMBL3836817 | 0.69 | TSHR (0.38) | TSHRTDP1 | |
| SCHEMBL2929567 | 0.69 | TSHR (0.38) | TSHRTDP1 | |
| SCHEMBL14244691 | 0.69 | TSHR (0.38) | TSHRTDP1 | |
| SCHEMBL2550050 | 0.69 | — | — | |
| SCHEMBL3835989 | 0.69 | TSHR (0.38) | TSHRTDP1 | |
| SCHEMBL2930618 | 0.69 | TSHR (0.38) | TSHRTDP1 | |
| Phosphine SCHEMBL23111707 | 0.67 | TSHR (0.35) | TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116693365-B | Preparation method and preparation device system of hexafluorobutadiene | 天津绿菱气体有限公司 | 2023-10-31 | — | — | CN | disclosed |
| CN-116693365-A | Preparation method and preparation device system of hexafluorobutadiene | 天津绿菱气体有限公司 | 2023-09-05 | — | — | CN | disclosed |
| EP-1534722-B1 | RHODIUM AND IRIDIUM COMPLEXES | MERCK PATENT GMBH (DE) | 2017-03-22 | — | — | EP | disclosed |
| US-9556211-B2 | Metal complex compound, hydrogen production catalyst and hydrogenation reaction catalyst each comprising the metal complex compound, and hydrogen production method and hydrogenation method each using the catalyst | NATIONAL UNIVERSITY CORPORATION OKAYAMA UNIVERSITY (JP) | 2017-01-31 | — | — | US | disclosed |
| US-20160264720-A1 | METHOD FOR THE PRODUCTION OF POLYMERS | MERCK PATENT GMBH (DE) | 2016-09-15 | — | — | US | disclosed |
| US-9415370-B2 | Method for the production of polymers | MERCK PATENT GMBH (DE) | 2016-08-16 | — | — | US | disclosed |
| EP-2552928-B1 | A PROCESS FOR THE REDUCTION OF A TERTIARY PHOSPHINE OXIDE TO THE CORRESPONDING TERTIARY PHOSPHINE IN THE PRESENCE OF A CATALYST AND USE OF A TERTIARY PHOSPHINE FOR REDUCING A TERTIARY PHOSPHINE OXIDE IN THE PRESENCE OF A CATALYST. | CHROMAFORA AB (SE) | 2015-04-15 | — | — | EP | disclosed |
| US-8735629-B2 | Process for the reduction of a tertiary phosphine oxide to the corresponding tertiary phosphine in the presence of a catalyst and use of a tertiary phosphine for reducing a tertiary phosphine oxide in the presence of a catalyst | CHROMAFORA AB (SE) | 2014-05-27 | — | — | US | disclosed |
| EP-2289902-B1 | Rhodium and iridium complexes | MERCK PATENT GMBH (DE) | 2014-04-30 | — | — | EP | disclosed |
| EP-2644611-A1 | METAL COMPLEX COMPOUND, HYDROGEN PRODUCTION CATALYST AND HYDROGENATION REACTION CATALYST EACH COMPRISING THE METAL COMPLEX COMPOUND, AND HYDROGEN PRODUCTION METHOD AND HYDROGENATION METHOD EACH USING THE CATALYST | National University Corporation Okayama University (JP) | 2013-10-02 | — | — | EP | disclosed |
| EP-1379534-B1 | RHODIUM AND IRIDIUM COMPLEXES | COVION ORGANIC SEMICONDUCTORS (DE) | 2004-12-15 | — | — | EP | disclosed |
| US-20040133004-A1 | Rhodium and iridium complexes | MERCK PATENT GMBH (DE) | 2004-07-08 | — | — | US | disclosed |
| US-20030229240-A1 | Reacting phosphorus halide with organomagnesium compound in presence of copper compound | LANXESS DEUTSCHLAND GMBH (DE) | 2003-12-11 | — | — | US | disclosed |
| EP-1354886-A1 | Process for the preparation of tertiary phosphines | Bayer Aktiengesellschaft (DE) | 2003-10-22 | — | — | EP | disclosed |
| WO-2003084972-A1 | RHODIUM COMPLEXES AND IRIDIUM COMPLEXES | COVION ORGANIC SEMICONDUCTORS GMBH (DE) | 2003-10-16 | — | — | WO | disclosed |
| US-20020165411-A1 | Sterically hindered phosphine ligands and uses thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2002-11-07 | — | — | US | disclosed |
| WO-2002048160-A1 | STERICALLY HINDERED PHOSPHINE LIGANDS AND USES THEREOF | YALE UNIVERSITY (US) | 2002-06-20 | — | — | WO | disclosed |
| US-4721683-A | LIQUID PHASE | AMERICAN CYANAMID COMPANY (US) | 1988-01-26 | — | — | US | disclosed |
| US-4595701-A | Reacting carbon monoxide and hydrogen in liquid phase in the presence of a rhodium and trialkylphosphine catalyst | AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 1986-06-17 | — | — | US | disclosed |
| US-4504674-A | METAL TREATED RUTHENIUM CATALYST | E. I. DUPONT DE NEMOURS & CO. (US) | 1985-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020165411-A1 | Sterically hindered phosphine ligands and uses thereof | NRP1, NR2C2, CXCR1 | TSHR 841/4885TDP1 4525/4885ALDH1A1 3092/4885 |
| US-20040133004-A1 | Rhodium and iridium complexes | RPIA, SIRT5, INPP5B | TSHR 2691/4885TDP1 1719/4885ALDH1A1 1115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.