Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.42 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.42 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11558688 | 0.85 | SIRT2 (0.45) | ELANEMAPTALDH1A1KMT2AHPGD | |
| SCHEMBL11563358 | 0.83 | GAA (0.58) | ELANEMAPTGAAALDH1A1HSP90AA1 | |
| SCHEMBL11553985 | 0.83 | MAPT (0.52) | ELANEMAPTGAAALDH1A1HSP90AA1 | |
| SCHEMBL11558765 | 0.83 | ELANE (0.43) | ELANEMAPTGAAALDH1A1HSP90AA1 | |
| SCHEMBL6558610 | 0.83 | MAPT (0.70) | ELANEMAPTGAAALDH1A1HSP90AA1 | |
| SCHEMBL22258850 | 0.83 | MAPT (0.58) | ELANEMAPTGAAALDH1A1HSP90AA1 | |
| SCHEMBL11553999 | 0.80 | LMNA (0.52) | ELANEMAPTGAAALDH1A1HSP90AA1 | |
| SCHEMBL11558538 | 0.80 | GAA (0.54) | MAPTGAAKMT2ANPC1RAB9A | |
| SCHEMBL12258167 | 0.79 | MAPT (0.59) | ELANEMAPTGAAALDH1A1HSP90AA1 | |
| SCHEMBL2840055 | 0.79 | MAOA (0.45) | ELANEMAPTGAAALDH1A1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4147880-A | Age resisters and age resistant polymeric compositions | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1979-04-03 | — | — | US | disclosed |
| US-3953411-A | Age resistant polymers of 4-(arylamino)aryl esters of α,β unsaturated carboxylic acids | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1976-04-27 | — | — | US | disclosed |