Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | PRKCI | P41743 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA7 | P43166 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.38 |
| ▸ | CA3 | P07451 | 2/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | CA6 | P23280 | 2/20 | 0.38 |
| ▸ | CA5A | P35218 | 2/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28503260 | 0.86 | ALDH1A1 (0.58) | ALDH1A1PRKCIPTPN1PTPN11RXRA | |
| SCHEMBL9376210 | 0.81 | PTPN1 (0.50) | ALDH1A1PRKCIPTPN1PTPN11CA5A | |
| SCHEMBL10487676 | 0.78 | ALDH1A1 (0.46) | ALDH1A1PRKCIPTPN1PTPN11RXRA | |
| SCHEMBL10690373 | 0.76 | MEN1 (0.53) | PRKCIGRM2LMNAMAPTMEN1 | |
| SCHEMBL25619130 | 0.75 | GABRA1 (0.45) | ALDH1A1PTPN1PTPN11CA12CA1 | |
| SCHEMBL3547229 | 0.75 | CA12 (0.66) | CA12CA1CA2CA7CA9 | |
| SCHEMBL6067636 | 0.75 | ALDH1A1 (0.55) | ALDH1A1CA12CA1CA2CA7 | |
| SCHEMBL27787365 | 0.74 | TPMT (0.46) | ALDH1A1PTPN1PTPN11RXRACA12 | |
| SCHEMBL40166 | 0.74 | PTPN1 (0.59) | ALDH1A1PRKCIPTPN1PTPN11HPGD | |
| SCHEMBL7648311 | 0.73 | PPARG (0.41) | PRKCIGRM2CA9LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4148900-A | ANTIALLERGIC | CARLO ERBA S.P.A. (IT) | 1979-04-10 | — | — | US | disclosed |