Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11563944 | 0.75 | PTGS1 (0.40) | PTGS1PTGS2 | |
| SCHEMBL10662292 | 0.75 | PPARG (0.42) | TP53 | |
| SCHEMBL11559592 | 0.74 | CYP17A1 (0.37) | PTGS1PTGS2 | |
| SCHEMBL11557734 | 0.74 | HTR2A (0.39) | GAA | |
| SCHEMBL11560451 | 0.73 | HSD17B10 (0.43) | PTGS1PTGS2TP53 | |
| SCHEMBL11561802 | 0.72 | ESR1 (0.33) | — | |
| SCHEMBL11559332 | 0.71 | ESR1 (0.42) | — | |
| SCHEMBL11560465 | 0.71 | PTGS1 (0.36) | PTGS1 | |
| SCHEMBL11558151 | 0.71 | KMT2A (0.41) | PTGS1PTGS2 | |
| SCHEMBL11558789 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0002666-A1 | 1,2-Benzisoxazolyloxy (or thio) acetic acids and related compounds, process for their preparation and medicines containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-07-11 | — | — | EP | disclosed |