Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | GPBAR1 | Q8TDU6 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11558673 | 0.85 | PTGS1 (0.45) | PTGS1CYP17A1HTR7GPBAR1MAPT | |
| SCHEMBL11557764 | 0.85 | ESR1 (0.40) | HSD17B10CYP17A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL11557670 | 0.85 | CYP17A1 (0.41) | HSD17B10PTGS1PTGS2CYP17A1GPBAR1 | |
| SCHEMBL11554808 | 0.81 | GPBAR1 (0.42) | GPBAR1SMN1; SMN2 | |
| SCHEMBL11563201 | 0.80 | PTGS1 (0.38) | PTGS1CYP17A1HTR7GPBAR1MAPT | |
| SCHEMBL11559592 | 0.80 | CYP17A1 (0.37) | HSD17B10PTGS1PTGS2CYP17A1GPBAR1 | |
| SCHEMBL11559267 | 0.78 | GRM5 (0.37) | HSD17B10LMNAMAPTSMN1; SMN2TP53 | |
| SCHEMBL11557734 | 0.76 | HTR2A (0.39) | HTR7GPBAR1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL11560465 | 0.76 | PTGS1 (0.36) | PTGS1GPBAR1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL11558151 | 0.76 | KMT2A (0.41) | HSD17B10PTGS1PTGS2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0002666-A1 | 1,2-Benzisoxazolyloxy (or thio) acetic acids and related compounds, process for their preparation and medicines containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-07-11 | — | — | EP | disclosed |