Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 3/20 | 0.36 |
| ▸ | HTR2C | P28335 | 3/20 | 0.36 |
| ▸ | HTR2B | P41595 | 3/20 | 0.36 |
| ▸ | TERT | O14746 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 2/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11565003 | 0.80 | NOS3 (0.36) | GAAMAPTKDM4ELMNAPARP1 | |
| SCHEMBL11561840 | 0.80 | TSHR (0.39) | KMT2AMEN1GAAMAPTALDH1A1 | |
| SCHEMBL11559379 | 0.76 | CYP19A1 (0.41) | KMT2AMEN1GAAMAPTKDM4E | |
| SCHEMBL11564273 | 0.75 | DAO (0.38) | GAAMAPTALDH1A1L3MBTL1DAO | |
| SCHEMBL11560238 | 0.73 | KDM4E (0.35) | KMT2AMEN1GAAMAPTKDM4E | |
| SCHEMBL11557884 | 0.72 | HTR2A (0.38) | KMT2AMEN1GAAMAPTKDM4E | |
| SCHEMBL11556910 | 0.71 | SCN9A (0.39) | ALDH1A1TERTHCRTR2RIPK1IDH1 | |
| SCHEMBL11559070 | 0.68 | SCN9A (0.38) | KDM4EALDH1A1HCRTR2LMNA | |
| SCHEMBL13595220 | 0.67 | HTR2C (0.66) | HTR2AHTR2CHTR2B | |
| SCHEMBL11556049 | 0.66 | SIRT2 (0.33) | KMT2AMEN1MAPTALDH1A1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4134974-A | Imidazo[5,1-c][1,4]benzoxazin-1-one | CARLO ERBA S. P. A. (IT) | 1979-01-16 | — | — | US | disclosed |