Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | PARP1 | P09874 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11562161 | 0.81 | RIPK1 (0.40) | SMN1; SMN2NPSR1ALDH1A1GAA | |
| SCHEMBL11561840 | 0.81 | TSHR (0.39) | SMN1; SMN2NPSR1ALDH1A1MAPTCYP3A4 | |
| SCHEMBL11557905 | 0.79 | MAOA (0.35) | CYP3A4PARP1 | |
| SCHEMBL11561229 | 0.79 | FABP6 (0.38) | DAOSMN1; SMN2NPSR1PARP1 | |
| SCHEMBL11565003 | 0.79 | NOS3 (0.36) | LMNAMAPTPARP1GAA | |
| SCHEMBL11559379 | 0.78 | CYP19A1 (0.41) | SMN1; SMN2LMNANPSR1ALDH1A1MAPT | |
| SCHEMBL11560280 | 0.75 | KMT2A (0.42) | DAOHCRTR2LMNAALDH1A1MAPT | |
| SCHEMBL11555523 | 0.75 | HCRTR2 (0.38) | DAOHCRTR2SMN1; SMN2LMNANPSR1 | |
| SCHEMBL7471047 | 0.75 | NOTUM (0.43) | SMN1; SMN2LMNANPSR1ALDH1A1MAPT | |
| SCHEMBL11563044 | 0.74 | CYP1A2 (0.46) | SMN1; SMN2NPSR1ALDH1A1MAPTCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4134974-A | Imidazo[5,1-c][1,4]benzoxazin-1-one | CARLO ERBA S. P. A. (IT) | 1979-01-16 | — | — | US | disclosed |