Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 2/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11561840 | 0.83 | TSHR (0.39) | PARP1GAAMAPT | |
| SCHEMBL11557905 | 0.83 | MAOA (0.35) | PARP1CHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL11561229 | 0.83 | FABP6 (0.38) | PARP1 | |
| SCHEMBL11560280 | 0.80 | KMT2A (0.42) | PARP1GAAMAPTKDM4ELMNA | |
| SCHEMBL11559379 | 0.80 | CYP19A1 (0.41) | GAAMAPTKDM4ELMNA | |
| SCHEMBL7471047 | 0.79 | NOTUM (0.43) | GAAMAPTNOTUMLMNA | |
| SCHEMBL11564273 | 0.79 | DAO (0.38) | PARP1GAAMAPTLMNA | |
| SCHEMBL11563044 | 0.76 | CYP1A2 (0.46) | CHRNB4CHRNA3CHRNB2CHRNA4GAA | |
| SCHEMBL11562161 | 0.76 | RIPK1 (0.40) | GAA | |
| SCHEMBL11557177 | 0.70 | CHEK1 (0.34) | NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4134974-A | Imidazo[5,1-c][1,4]benzoxazin-1-one | CARLO ERBA S. P. A. (IT) | 1979-01-16 | — | — | US | disclosed |