Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 7/20 | 0.47 |
| ▸ | NPC1 | O15118 | 7/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.47 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11556621 | 0.88 | NR1H3 (0.61) | TDP2RAB9ANPC1NR1H2NR1H3 | |
| SCHEMBL11553037 | 0.88 | NR1H3 (0.48) | TDP2RAB9ANPC1NR1H2NR1H3 | |
| SCHEMBL11621091 | 0.87 | TDP2 (0.48) | TDP2RAB9ANPC1NR1H2NR1H3 | |
| SCHEMBL11553898 | 0.85 | TDP2 (0.46) | TDP2RAB9ANPC1NR1H2NR1H3 | |
| SCHEMBL11553734 | 0.82 | TDP2 (0.53) | TDP2RAB9ANPC1NR1H2NR1H3 | |
| SCHEMBL12434742 | 0.77 | FFAR1 (0.45) | RAB9ANPC1MAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL11560320 | 0.76 | RAB9A (0.43) | RAB9ANPC1NR1H2NR1H3MAPT | |
| SCHEMBL11555296 | 0.74 | NR1H3 (0.61) | TDP2RAB9ANPC1NR1H2NR1H3 | |
| SCHEMBL11555110 | 0.73 | NR1H2 (0.46) | RAB9ANPC1NR1H2NR1H3HSD17B2 | |
| SCHEMBL8301501 | 0.73 | RAB9A (0.51) | TDP2RAB9ANPC1NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4151169-A | DECYCLIZATION, CYCLIZATION | GRUPPO LEPETIT (IT) | 1979-04-24 | — | — | US | disclosed |
| US-4119635-A | SEDATIVES, HYPNOTICS, TRANQUILIZERS | GRUPPO LEPETIT S.P.A. (IT) | 1978-10-10 | — | — | US | disclosed |