Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11557677 | 0.88 | RAB9A (0.43) | RAB9ANR1H2NR1H3NPC1ALDH1A1 | |
| SCHEMBL11556621 | 0.84 | NR1H3 (0.61) | RAB9ANR1H2NR1H3NPC1ALDH1A1 | |
| SCHEMBL11552816 | 0.83 | KMT2A (0.42) | RAB9ANR1H2NR1H3NPC1ALDH1A1 | |
| SCHEMBL9829125 | 0.79 | ALDH1A1 (0.44) | RAB9ANR1H2NR1H3NPC1ALDH1A1 | |
| SCHEMBL11556785 | 0.76 | MEN1 (0.49) | RAB9ANPC1ALDH1A1PKMKMT2A | |
| SCHEMBL11560347 | 0.76 | TDP2 (0.48) | RAB9ANR1H2NR1H3NPC1ALDH1A1 | |
| SCHEMBL11553037 | 0.74 | NR1H3 (0.48) | RAB9ANR1H2NR1H3NPC1ALDH1A1 | |
| SCHEMBL29019620 | 0.72 | PDCD1 (0.42) | SIRT2ADORA3ADORA2AAR | |
| SCHEMBL11555296 | 0.71 | NR1H3 (0.61) | RAB9ANR1H2NR1H3NPC1ALDH1A1 | |
| SCHEMBL11556472 | 0.69 | NR1H3 (0.58) | RAB9ANR1H2NR1H3NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4151169-A | DECYCLIZATION, CYCLIZATION | GRUPPO LEPETIT (IT) | 1979-04-24 | — | — | US | disclosed |