Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PTPRA | P18433 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL28775065 | 0.98 | CYP1A2 (0.50) | HTTKDM4ECYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL27679728 | 0.90 | HRH1 (0.53) | HTTCYP1A2CYP2C19ALDH1A1NPC1 | |
| SCHEMBL951055 | 0.88 | HRH1 (0.55) | HTTCYP1A2CYP2C19ALDH1A1NPC1 | |
| Oxalic Acid SCHEMBL1156033 | 0.83 | ALDH1A1 (0.57) | KDM4ECYP1A2CYP2C19SMN1; SMN2MAPK1 | |
| Oxalic Acid SCHEMBL27733515 | 0.81 | ALDH1A1 (0.58) | KDM4ECYP1A2CYP2C19SMN1; SMN2MAPK1 | |
| Oxalic Acid SCHEMBL27733516 | 0.81 | ALDH1A1 (0.58) | KDM4ECYP1A2CYP2C19SMN1; SMN2MAPK1 | |
| SCHEMBL28723685 | 0.78 | HTT (0.51) | HTTMAPK1ALDH1A1NPC1RAB9A | |
| SCHEMBL949945 | 0.78 | HRH1 (0.55) | CYP1A2CYP2C19SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL29993219 | 0.77 | ALDH1A1 (0.53) | HTTCYP1A2CYP2C19SMN1; SMN2MAPK1 | |
| SCHEMBL177882 | 0.77 | ALDH1A1 (0.53) | HTTCYP1A2CYP2C19SMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2011798-B1 | Preparation of platinum (II) complexes | PLATCO TECHNOLOGIES PROPRIETARY LTD (ZA) | 2011-06-29 | — | — | EP | disclosed |
| US-7888523-B2 | Preparation of platinum(II) complexes | PLATCO TECHNOLOGIES (PROPRIETARY) LIMITED (ZA) | 2011-02-15 | — | — | US | disclosed |
| US-20090299085-A1 | PREPARATION OF PLATINUM(II) COMPLEXES | PLATCO TECHNOLOGIES (PROPRIETARY) LIMITED (ZA) | 2009-12-03 | — | — | US | disclosed |
| US-7589225-B2 | Preparation of platinum(II) complexes | PLATCO TECHNOLOGIES (PROPRIETARY) LIMITED (ZA) | 2009-09-15 | — | — | US | disclosed |
| EP-1789427-B1 | PREPARATION OF PLATINUM(II) COMPLEXES | PLATCO TECHNOLOGIES PROPRIETAR (ZA) | 2009-05-20 | — | — | EP | disclosed |
| EP-2011798-A1 | Preparation of platinum (II) complexes | Platco Technologies (Proprietary) Limited (ZA) | 2009-01-07 | — | — | EP | disclosed |
| US-20080064895-A1 | Preparation of Platinum(II) Complexes | PLATCO TECHNOLOGIES (PROPRIETARY) LIMITED (ZA) | 2008-03-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090299085-A1 | PREPARATION OF PLATINUM(II) COMPLEXES | SLCO4C1, OTC, SLC10A6 | HTT 1725/4885KDM4E 4208/4885CYP1A2 1404/4885 |
| US-20080064895-A1 | Preparation of Platinum(II) Complexes | SLCO4C1, SLC10A6, OTC | HTT 1824/4885KDM4E 4200/4885CYP1A2 1425/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.