Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | PTPRA | P18433 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL27733516 | 0.98 | ALDH1A1 (0.58) | ALDH1A1CYP1A2TSHRMAPK1PTPRA | |
| Oxalic Acid SCHEMBL27733515 | 0.98 | ALDH1A1 (0.58) | ALDH1A1CYP1A2TSHRMAPK1PTPRA | |
| SCHEMBL27679733 | 0.89 | ALDH1A1 (0.53) | ALDH1A1CYP1A2TSHRLMNASMN1; SMN2 | |
| SCHEMBL30530922 | 0.87 | — | — | |
| SCHEMBL951074 | 0.87 | — | — | |
| Phosphonic Acid SCHEMBL9637894 | 0.84 | ALDH1A1 (0.54) | ALDH1A1CYP1A2TSHRMAPK1PTPRA | |
| Oxalic Acid SCHEMBL1156072 | 0.83 | HTT (0.49) | ALDH1A1CYP1A2TSHRMAPK1PTPRA | |
| Oxalic Acid SCHEMBL28775065 | 0.81 | CYP1A2 (0.50) | ALDH1A1CYP1A2TSHRMAPK1PTPRA | |
| SCHEMBL9637900 | 0.79 | ALDH1A1 (0.49) | ALDH1A1CYP1A2TSHRMAPK1LMNA | |
| Oxalic Acid SCHEMBL9231859 | 0.78 | PTPRA (0.53) | ALDH1A1CYP1A2TSHRPTPRASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7576126-B2 | Platinum (II) complexes, preparation and use | PLATCO TECHNOLOGIES (PROPRIETARY) LIMITED (ZA) | 2009-08-18 | — | — | US | claimed |
| US-20070167643-A1 | Platinum (II) complexes, preparation and use | PLATCO TECHNOLOGIES (PROPRIETARY) LIMITED (ZA) | 2007-07-19 | — | — | US | claimed |
| EP-2011798-B1 | Preparation of platinum (II) complexes | PLATCO TECHNOLOGIES PROPRIETARY LTD (ZA) | 2011-06-29 | — | — | EP | disclosed |
| EP-2330110-A1 | Platinum(II) complexes, preparation and use | Platco Technologies (Proprietary) Limited (ZA) | 2011-06-08 | — | — | EP | disclosed |
| US-7956208-B2 | Preparation of platinum (II) complexes | PLATCO TECHNOLOGIES (PROPRIETARY) LIMITED (ZA) | 2011-06-07 | — | — | US | disclosed |
| US-7888523-B2 | Preparation of platinum(II) complexes | PLATCO TECHNOLOGIES (PROPRIETARY) LIMITED (ZA) | 2011-02-15 | — | — | US | disclosed |
| US-7888390-B2 | Preparation of platinum(II) complexes | PLATCO TECHNOLOGIES (PROPRIETARY) LIMITED (ZA) | 2011-02-15 | — | — | US | disclosed |
| US-20090312417-A1 | PLATINUM(II) COMPLEXES, PREPARATION AND USE | PLATCO TECHNOLOGIES (PROPRIETARY) LIMITED (ZA) | 2009-12-17 | — | — | US | disclosed |
| US-20090281319-A1 | PREPARATION OF PLATINUM (II) COMPLEXES | PLATCO TECHNOLOGIES (PROPRIETARY) LIMITED (ZA) | 2009-11-12 | — | — | US | disclosed |
| US-7576126-B2 | Platinum (II) complexes, preparation and use | PLATCO TECHNOLOGIES (PROPRIETARY) LIMITED (ZA) | 2009-08-18 | — | — | US | disclosed |
| US-20070167643-A1 | Platinum (II) complexes, preparation and use | PLATCO TECHNOLOGIES (PROPRIETARY) LIMITED (ZA) | 2007-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090312417-A1 | PLATINUM(II) COMPLEXES, PREPARATION AND USE | PDCD5, ORC3, PDCD2L | ALDH1A1 3930/4885CYP1A2 1505/4885TSHR 4105/4885 |
| US-20070167643-A1 | Platinum (II) complexes, preparation and use | PDCD5, ORC3, PDCD2L | ALDH1A1 3930/4885CYP1A2 1505/4885TSHR 4105/4885 |
| US-20090281319-A1 | PREPARATION OF PLATINUM (II) COMPLEXES | OAT, OTC, POLR2E | ALDH1A1 1641/4885CYP1A2 511/4885TSHR 3211/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.