Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 1.00 |
| ▸ | HPGD | P15428 | 5/20 | 1.00 |
| ▸ | NFKB1 | P19838 | 2/20 | 1.00 |
| ▸ | NFKB2 | Q00653 | 2/20 | 1.00 |
| ▸ | RELA | Q04206 | 2/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 1.00 |
| ▸ | NPC1 | O15118 | 7/20 | 0.76 |
| ▸ | RAB9A | P51151 | 7/20 | 0.76 |
| ▸ | TP53 | P04637 | 3/20 | 0.76 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.76 |
| ▸ | CASP3 | P42574 | 6/20 | 0.71 |
| ▸ | SENP7 | Q9BQF6 | 5/20 | 0.71 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.71 |
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10218249 | 0.90 | SMN1; SMN2 (0.82) | KDM4EALDH1A1SMN1; SMN2HPGDNFKB1 | |
| SCHEMBL3288386 | 0.86 | ALDH1A1 (1.00) | KDM4EALDH1A1SMN1; SMN2HPGDNFKB1 | |
| SCHEMBL14947173 | 0.84 | ALDH1A1 (0.96) | KDM4EALDH1A1SMN1; SMN2HPGDNFKB1 | |
| SCHEMBL29622933 | 0.84 | KDM4E (0.72) | KDM4EALDH1A1SMN1; SMN2HPGDNFKB1 | |
| SCHEMBL29622897 | 0.84 | NPC1 (0.76) | KDM4EALDH1A1SMN1; SMN2HPGDNFKB1 | |
| SCHEMBL23748361 | 0.84 | KDM4E (0.72) | KDM4EALDH1A1SMN1; SMN2HPGDNFKB1 | |
| SCHEMBL10565801 | 0.84 | ESR1 (0.76) | KDM4EALDH1A1SMN1; SMN2HPGDNFKB1 | |
| SCHEMBL24881857 | 0.84 | SMN1; SMN2 (0.94) | KDM4EALDH1A1SMN1; SMN2HPGDNFKB1 | |
| SCHEMBL9115618 | 0.84 | SMN1; SMN2 (0.72) | KDM4EALDH1A1SMN1; SMN2HPGDNFKB1 | |
| SCHEMBL1734841 | 0.84 | NPC1 (0.76) | KDM4EALDH1A1SMN1; SMN2HPGDNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4169837-A | BICHROMOPHORIC BENZOXAZOLE ULTRAVIOLET STABILIZERS | EASTMAN KODAK COMPANY (US) | 1979-10-02 | — | — | US | disclosed |
| US-4029670-A | Polychromophoric heterocyclic ultraviolet stabilizers | EASTMAN KODAK COMPANY (US) | 1977-06-14 | — | — | US | disclosed |