SCHEMBL14947173

SCHEMBL14947173

Cc1ccc2oc(-c3ccc(-c4nc5cc(C)ccc5o4)cc3)nc2c1

nearest known ligand 0.96

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 13/20 0.96
KDM4E B2RXH2 12/20 0.96
RAB9A P51151 12/20 0.96
SMN1; SMN2 Q16637 11/20 0.96
NPC1 O15118 11/20 0.96
HPGD P15428 11/20 0.96
HSD17B10 Q99714 9/20 0.96
TP53 P04637 8/20 0.96
CASP3 P42574 4/20 0.83
SENP7 Q9BQF6 4/20 0.83
SENP6 Q9GZR1 4/20 0.83
SENP8 Q96LD8 3/20 0.83
POLB P06746 1/20 0.83
NFKB1 P19838 5/20 0.73
NFKB2 Q00653 5/20 0.73
RELA Q04206 5/20 0.73
MAPT P10636 5/20 0.73
L3MBTL1 Q9Y468 3/20 0.73
LMNA P02545 1/20 0.73
MMP2 P08253 1/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3288386 0.98 ALDH1A1 (1.00) ALDH1A1KDM4ERAB9ASMN1; SMN2NPC1
SCHEMBL15047797 0.98 ALDH1A1 (0.93) ALDH1A1KDM4ERAB9ASMN1; SMN2NPC1
SCHEMBL10045311 0.93 ALDH1A1 (0.84) ALDH1A1KDM4ERAB9ASMN1; SMN2NPC1
SCHEMBL10218249 0.92 SMN1; SMN2 (0.82) ALDH1A1KDM4ERAB9ASMN1; SMN2NPC1
SCHEMBL22103734 0.92 NPC1 (0.81) ALDH1A1KDM4ERAB9ASMN1; SMN2NPC1
SCHEMBL2760352 0.92 KDM4E (0.81) ALDH1A1KDM4ERAB9ASMN1; SMN2NPC1
SCHEMBL10061932 0.92 SMN1; SMN2 (0.81) ALDH1A1KDM4ERAB9ASMN1; SMN2NPC1
SCHEMBL474369 0.92 RAB9A (0.82) ALDH1A1KDM4ERAB9ASMN1; SMN2NPC1
SCHEMBL31154077 0.92 RAB9A (0.82) ALDH1A1KDM4ERAB9ASMN1; SMN2NPC1
SCHEMBL152658 0.91 SMN1; SMN2 (1.00) ALDH1A1KDM4ERAB9ASMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9318705-B2 Organic light emitting device with roughening layer and method of producing NOVALED GMBH (DE) 2016-04-19 US disclosed
US-9318705-B2 Organic light emitting device with roughening layer and method of producing NOVALED GMBH (DE) 2016-04-19 US disclosed
US-9214692-B2 Poly(benzimidazole-co-benzoxazole) and method for preparing the same KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2015-12-15 US disclosed
US-9146483-B2 Photoreceptor, method for preparing photoreceptor, and image forming apparatus and process cartridge using the photoreceptor RICOH COMPANY, LTD. (JP) 2015-09-29 US disclosed
US-9146483-B2 Photoreceptor, method for preparing photoreceptor, and image forming apparatus and process cartridge using the photoreceptor RICOH COMPANY, LTD. (JP) 2015-09-29 US disclosed
US-20140332794-A1 Organic Light Emitting Device and Method of Producing NOVALED GMBH (DE) 2014-11-13 US disclosed
US-20140332794-A1 Organic Light Emitting Device and Method of Producing NOVALED GMBH (DE) 2014-11-13 US disclosed
US-20140234763-A1 IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2014-08-21 US disclosed
US-20140234763-A1 IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2014-08-21 US disclosed
US-20130243483-A1 PHOTORECEPTOR, METHOD FOR PREPARING PHOTORECEPTOR, AND IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE USING THE PHOTORECEPTOR RICOH COMPANY, LTD. (JP) 2013-09-19 US disclosed
US-20130243483-A1 PHOTORECEPTOR, METHOD FOR PREPARING PHOTORECEPTOR, AND IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE USING THE PHOTORECEPTOR RICOH COMPANY, LTD. (JP) 2013-09-19 US disclosed
US-20130122410-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE FOR IMAGE FORMING APPARATUS USING THE ELCTROPHOTOGRAPHIC PHOTOCONDUCTOR RICOH COMPANY, LTD. (JP) 2013-05-16 US disclosed
US-20130122410-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE FOR IMAGE FORMING APPARATUS USING THE ELCTROPHOTOGRAPHIC PHOTOCONDUCTOR RICOH COMPANY, LTD. (JP) 2013-05-16 US disclosed