Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11566800 | 1.00 | MTNR1A (0.37) | MTNR1AMTNR1BTSHRNPSR1GAA | |
| SCHEMBL15110135 | 0.81 | GAA (0.42) | TSHRNPSR1GAAMAPTMAOA | |
| SCHEMBL27348749 | 0.81 | GAA (0.42) | TSHRNPSR1GAAMAPTMAOA | |
| SCHEMBL3519807 | 0.70 | RAB9A (0.48) | MTNR1AMTNR1BAKR1C3AKR1C1ANPEP | |
| SCHEMBL15049345 | 0.69 | MTNR1A (0.40) | MTNR1AMTNR1BTSHRGAAMAPT | |
| SCHEMBL27277678 | 0.69 | MAOA (0.36) | MTNR1AMTNR1BMAOAMAOBAKR1C3 | |
| SCHEMBL18243384 | 0.68 | PLAU (0.38) | TSHRMAOBANPEPPLAU | |
| SCHEMBL17765413 | 0.68 | PLAU (0.38) | TSHRMAOBANPEPPLAU | |
| SCHEMBL18378200 | 0.68 | PLAU (0.38) | TSHRMAOBANPEPPLAU | |
| SCHEMBL15049696 | 0.68 | MAOB (0.39) | MTNR1AMTNR1BMAOBPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4152527-A | 15-Substituted-ω-pentanorprostaglandins | PFIZER INC. (US) | 1979-05-01 | — | — | US | disclosed |