Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
| ▸ | FABP4 | P15090 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7517048 | 0.73 | FABP4 (0.61) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL7511654 | 0.72 | FABP4 (0.59) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL17101162 | 0.70 | L3MBTL1 (0.59) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL11560895 | 0.70 | FABP4 (0.61) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL11435219 | 0.70 | L3MBTL1 (0.57) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL7511658 | 0.70 | FABP4 (0.61) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL11495820 | 0.69 | FABP4 (0.59) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL4258883 | 0.69 | FABP4 (0.59) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL422151 | 0.67 | CA1 (0.63) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL7517054 | 0.67 | F2 (0.41) | CA1CA2MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0000826-A1 | Diorthosubstituted benzene derivatives, especially for use in a method of therapy, processes for their preparation, and pharmaceutical compositions containing them | Kabi AB (SE) | 1979-02-21 | — | — | EP | disclosed |