Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.63 |
| ▸ | CA2 | P00918 | 1/20 | 0.63 |
| ▸ | MMP1 | P03956 | 1/20 | 0.63 |
| ▸ | MMP2 | P08253 | 1/20 | 0.63 |
| ▸ | MMP9 | P14780 | 1/20 | 0.63 |
| ▸ | MMP8 | P22894 | 1/20 | 0.63 |
| ▸ | MMP13 | P45452 | 1/20 | 0.63 |
| ▸ | F2 | P00734 | 3/20 | 0.56 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.56 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.56 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1868097 | 0.81 | GAA (0.43) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL813077 | 0.79 | CA1 (0.65) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL123883 | 0.77 | CA1 (1.00) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL812692 | 0.77 | CA1 (0.63) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL12353346 | 0.77 | CA1 (0.63) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL28192865 | 0.77 | CA1 (0.63) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL1868304 | 0.77 | TSHR (0.40) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL12098068 | 0.77 | ALDH1A1 (0.46) | CA1CA2MMP1MMP2MMP9 | |
| Water SCHEMBL9033021 | 0.76 | CA1 (0.96) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL5562243 | 0.76 | L3MBTL1 (0.67) | CA1CA2MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 209 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119529255-A | Preparation and application of degradable polyester and radiation-proof material based on methylparaben | 武汉科技大学 | 2025-02-28 | — | — | CN | claimed |
| EP-3670490-B1 | METHOD OF PURIFYING PINE CHEMICAL COMPOSITIONS FROM ALDEHYDES | KRATON POLYMERS LLC (US) | 2023-01-18 | — | — | EP | claimed |
| CN-110003160-B | Osthole hydrazone/acylhydrazone/sulfonylhydrazone derivatives, and preparation method and application thereof | 贵州中医药大学 | 2022-10-11 | — | — | CN | claimed |
| CN-112724132-B | Synthetic method of 3-halogenated-5-trifluoromethyl-pyrazolo [1,5-a ] pyridine | 药雅科技(上海)有限公司 | 2022-05-20 | — | — | CN | claimed |
| CN-114182271-A | Electrochemical synthesis method of allyl sulfone compound | 上海应用技术大学 | 2022-03-15 | — | — | CN | claimed |
| CN-114014859-A | Triazole indolol compound and synthesis method thereof | 绍兴文理学院 | 2022-02-08 | — | — | CN | claimed |
| CN-112724132-A | Synthetic method of 3-halogenated-5-trifluoromethyl-pyrazolo [1,5-a ] pyridine | 药雅科技(上海)有限公司 | 2021-04-30 | — | — | CN | claimed |
| CN-110590667-B | 3-trifluoromethyl substituted pyrazole derivative and synthesis method and application thereof | 华南理工大学 | 2020-12-22 | — | — | CN | claimed |
| CN-108059599-B | Preparation method of Venetong key intermediate | 凯方医药科技（上海）有限公司 | 2020-08-21 | — | — | CN | claimed |
| EP-3670490-A1 | METHOD OF PURIFYING PINE CHEMICAL COMPOSITIONS FROM ALDEHYDES | Kraton Polymers LLC (US) | 2020-06-24 | — | — | EP | claimed |
| US-20200165191-A1 | Method of Purifying Pine Chemical Compositions from Aldehydes | KRATON POLYMERS LLC (US) | 2020-05-28 | — | — | US | claimed |
| CN-110590667-A | 3-trifluoromethyl substituted pyrazole derivative and synthesis method and application thereof | 华南理工大学 | 2019-12-20 | — | — | CN | claimed |
| CN-110003160-A | A kind of Osthole hydrazone class/acylhydrazone class/sulphur acylhydrazone and preparation method thereof and application | 贵州中医药大学 | 2019-07-12 | — | — | CN | claimed |
| CN-108059599-A | A kind of preparation method of Wei Naituoke key intermediates | 凯方医药科技（上海）有限公司 | 2018-05-22 | — | — | CN | claimed |
| EP-1472259-B1 | TETRAPYRROLIC MACROCYCLES AS PHOTODYNAMIC AGENTS | CIPAN COMP IND PROD (PT) | 2009-09-02 | — | — | EP | claimed |
| EP-1436371-A2 | ENZYMATIC SYSTEMS FOR GENERATING ACTIVE OXYGEN SPECIES FOR REACTING WITH OTHER PRECURSORS TO OBTAIN OXIDATION AND/OR BLEACHING | Call, Krimhild (DE) | 2004-07-14 | — | — | EP | claimed |
| WO-2002099023-A2 | ENZYMATIC SYSTEMS FOR GENERATING ACTIVE OXYGEN SPECIES FOR REACTING WITH OTHER PRECURSORS TO OBTAIN OXIDATION AND/OR BLEACHING | CALL, KRIMHILD (DE) | 2002-12-12 | — | — | WO | claimed |
| US-12617774-B2 | Substituted indole compounds and methods of use thereof | NOVARTIS AG (CH) | 2026-05-05 | — | — | US | disclosed |
| EP-0536426-A1 | NOVEL CYCLOHEXENE DERIVATIVE AND PRODUCTION THEREOF | JAPAN TOBACCO INC. (JP) | 1993-04-14 | — | — | EP | disclosed |
| US-4218465-A | Glyoxylic acid hydrocarbylsulfonylhydrazones and therapeutic compositions | SRI INTERNATIONAL (US) | 1980-08-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12617774-B2 | Substituted indole compounds and methods of use thereof | CFB, CFD, TFPI | CA1 4201/4885CA2 2466/4885MMP1 966/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.