Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11427641 | 0.85 | ACE (0.42) | TDP1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11560085 | 0.84 | ACE (0.41) | TDP1 | |
| SCHEMBL11428707 | 0.76 | CA9 (0.41) | TDP1ALDH1A1 | |
| SCHEMBL7458698 | 0.75 | MCHR1 (0.53) | TDP1ATMALDH1A1GBA1 | |
| SCHEMBL11557147 | 0.70 | ACE (0.53) | — | |
| SCHEMBL11557917 | 0.69 | FKBP1A (0.40) | TDP1 | |
| SCHEMBL11554022 | 0.69 | BRD4 (0.38) | TDP1ALDH1A1MAPTHPGDRAB9A | |
| SCHEMBL9782021 | 0.68 | ALDH1A1 (0.55) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL6141087 | 0.68 | TDP1 (0.59) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL28659822 | 0.68 | TDP1 (0.54) | TDP1ATMALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4147787-A | ANTICOAGULANTS | PARCOR (FR) | 1979-04-03 | — | — | US | disclosed |