Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 12/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | ICMT | O60725 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL544817 | 0.74 | TLR8 (0.53) | TLR8KMT2ATDP1 | |
| SCHEMBL11746748 | 0.74 | SQOR (0.41) | L3MBTL1CYP1A2CYP2C19MEN1KMT2A | |
| SCHEMBL9470636 | 0.73 | TLR8 (0.51) | TLR8KMT2ATDP1 | |
| SCHEMBL11619066 | 0.73 | TLR8 (0.51) | TLR8KMT2ATDP1 | |
| SCHEMBL25939122 | 0.72 | ALDH1A1 (0.44) | TLR8KMT2ATDP1 | |
| SCHEMBL11078598 | 0.70 | TLR8 (0.41) | TLR8NPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL1844669 | 0.70 | CCNA2 (0.37) | — | |
| SCHEMBL18050888 | 0.70 | TLR8 (0.42) | TLR8CNR1ICMTNPC1RAB9A | |
| SCHEMBL7988227 | 0.70 | TLR8 (0.45) | TLR8CNR1ICMTNPC1RAB9A | |
| SCHEMBL11381033 | 0.69 | TLR8 (0.40) | TLR8KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4154841-A | Antiinflammatory 1-acyl-3(5)-alkyl-5(3)-phenyl-1,2,4-triazoles | E. R. SQUIBB & SONS, INC. (US) | 1979-05-15 | — | — | US | disclosed |