Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 18/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11619066 | 1.00 | TLR8 (0.51) | TLR8ALDH1A1TDP1KMT2A | |
| SCHEMBL544817 | 0.98 | TLR8 (0.53) | TLR8ALDH1A1TDP1KMT2A | |
| SCHEMBL11381033 | 0.78 | TLR8 (0.40) | TLR8ALDH1A1TDP1KMT2A | |
| SCHEMBL25939122 | 0.77 | ALDH1A1 (0.44) | TLR8ALDH1A1TDP1KMT2A | |
| SCHEMBL28114461 | 0.76 | TLR8 (0.39) | TLR8ALDH1A1TDP1 | |
| SCHEMBL16401247 | 0.76 | — | — | |
| SCHEMBL11078598 | 0.76 | TLR8 (0.41) | TLR8ALDH1A1TDP1KMT2A | |
| SCHEMBL1083103 | 0.74 | TLR8 (0.40) | TLR8ALDH1A1TDP1KMT2A | |
| SCHEMBL14442004 | 0.74 | AMPD1 (0.37) | TLR8ALDH1A1TDP1 | |
| SCHEMBL11561983 | 0.73 | TLR8 (0.46) | TLR8TDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5185358-A | Anticholesterol agents | WARNER-LAMBERT CO. (US) | 1993-02-09 | — | — | US | disclosed |