Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | HTT | P42858 | 2/20 | 0.69 |
| ▸ | EGFR | P00533 | 2/20 | 0.57 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 2/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | MMP9 | P14780 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11562991 | 1.00 | MAPT (0.69) | MAPTALDH1A1HTTEGFRDDAH1 | |
| SCHEMBL15708598 | 0.90 | EGFR (0.66) | MAPTALDH1A1HTTEGFRCA12 | |
| SCHEMBL15708595 | 0.90 | EGFR (0.66) | MAPTALDH1A1HTTEGFRCA12 | |
| SCHEMBL14683832 | 0.90 | ALDH1A1 (0.61) | MAPTALDH1A1HTTEGFRDDAH1 | |
| SCHEMBL19067081 | 0.83 | EGFR (0.63) | MAPTALDH1A1HTTEGFRMEN1 | |
| SCHEMBL9354309 | 0.83 | EGFR (0.63) | MAPTALDH1A1HTTEGFRMEN1 | |
| SCHEMBL9354315 | 0.83 | EGFR (0.63) | MAPTALDH1A1HTTEGFRMEN1 | |
| SCHEMBL21954812 | 0.80 | ALDH1A1 (0.57) | MAPTALDH1A1HTTEGFRDDAH1 | |
| SCHEMBL2429556 | 0.78 | ALDH1A1 (0.81) | MAPTALDH1A1HTTEGFRDDAH1 | |
| SCHEMBL9245082 | 0.78 | DDAH1 (0.69) | MAPTALDH1A1HTTEGFRDDAH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4179444-A | Process for the manufacture of iso-imides or mixtures of iso-imides and imides | CIBA-GEIGY CORPORATION (US) | 1979-12-18 | — | — | US | disclosed |