Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDAH1 | O94760 | 1/20 | 0.69 |
| ▸ | HTT | P42858 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | NMT1 | P30419 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 2/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7825460 | 0.83 | NMT1 (0.68) | HTTMAPTALDH1A1LMNANMT1 | |
| SCHEMBL7825464 | 0.83 | NMT1 (0.68) | HTTMAPTALDH1A1LMNANMT1 | |
| SCHEMBL28364040 | 0.83 | DDAH1 (0.66) | DDAH1HTTMAPTALDH1A1LMNA | |
| SCHEMBL5177465 | 0.81 | DDAH1 (1.00) | DDAH1HTTMAPTALDH1A1LMNA | |
| SCHEMBL5177391 | 0.81 | DDAH1 (1.00) | DDAH1HTTMAPTALDH1A1LMNA | |
| SCHEMBL28100786 | 0.80 | ALDH1A1 (0.58) | DDAH1HTTMAPTALDH1A1LMNA | |
| SCHEMBL11141344 | 0.79 | NMT1 (0.68) | MAPTALDH1A1LMNANMT1MEN1 | |
| SCHEMBL11141342 | 0.79 | NMT1 (0.68) | MAPTALDH1A1LMNANMT1MEN1 | |
| SCHEMBL2429556 | 0.78 | ALDH1A1 (0.81) | DDAH1HTTMAPTALDH1A1LMNA | |
| SCHEMBL11562989 | 0.78 | MAPT (0.69) | DDAH1HTTMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5446106-A | Additional polymerizing a maleic anhydride with a dioxolane in presence of a free radical catalysts, futher reacting with primary amine | EASTMAN CHEMICAL COMPANY (US) | 1995-08-29 | — | — | US | disclosed |
| US-5418294-A | Clear films | EASTMAN CHEMICAL COMPANY (US) | 1995-05-23 | — | — | US | disclosed |
| WO-1994015976-A1 | COPOLYMERS OF VINYL DIOXOLANES AND IMIDIZED DERIVATIVES OF MALEIC ANHYDRIDE | EASTMAN CHEMICAL COMPANY (US) | 1994-07-21 | — | — | WO | disclosed |
| US-5304611-A | Can be cast as clear films or used as crosslinking agents | EASTMAN KODAK COMPANY (US) | 1994-04-19 | — | — | US | disclosed |