Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP15 | Q460N3 | 1/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.49 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | IL18 | Q14116 | 1/20 | 0.48 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.46 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.45 |
| ▸ | USP14 | P54578 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | LIPE | Q05469 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4801215 | 0.92 | CYP2A6 (0.50) | RAB9AMAPTKDM4ELMNAMAPK1 | |
| SCHEMBL6651458 | 0.87 | F10 (0.49) | PARP15PARP10PARP2RAB9AMAPT | |
| SCHEMBL11564197 | 0.85 | RAB9A (0.54) | PARP15PARP10PARP2RAB9AMAPT | |
| SCHEMBL10566464 | 0.83 | RAB9A (0.56) | RAB9AMAPTKDM4ELMNAPOLB | |
| SCHEMBL11244931 | 0.81 | NPC1 (0.56) | RAB9AMAPTLMNAMAPK1ALDH1A1 | |
| SCHEMBL20351641 | 0.81 | MAPT (0.44) | RAB9AMAPTKDM4EMEN1LMNA | |
| SCHEMBL6651903 | 0.80 | SLC6A4 (0.56) | PARP15PARP10PARP2RAB9AMAPT | |
| SCHEMBL6917099 | 0.80 | SRD5A2 (0.57) | PARP15PARP10PARP2RAB9AMAPT | |
| SCHEMBL181473 | 0.79 | HPGD (0.61) | PARP10RAB9AMAPTPOLBTBXAS1 | |
| SCHEMBL68851 | 0.79 | CYP4Z1 (0.62) | RAB9AMAPTKDM4EMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4168385-A | LOWERING OF STEROL AND TRIGLYCERIDE SERUM LEVELS | AMERICAN CYANAMID COMPANY (US) | 1979-09-18 | — | — | US | disclosed |
| US-4125729-A | Hypolipemic α-aryloxy para substituted phenyl acetic acid compounds | AMERICAN CYANAMID COMPANY (US) | 1978-11-14 | — | — | US | disclosed |