Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 3/20 | 0.57 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.56 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.56 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | IL18 | Q14116 | 1/20 | 0.54 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | FNTA | P49354 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL335492 | 0.89 | CTBP2 (0.62) | LMNACTBP2FFAR1MMP2HTT | |
| SCHEMBL29236556 | 0.87 | CTBP2 (0.61) | LMNACTBP2FFAR1MMP2HTT | |
| Hydrochloric Acid SCHEMBL7981327 | 0.87 | CTBP2 (0.61) | LMNACTBP2FFAR1MMP2HTT | |
| SCHEMBL2999416 | 0.85 | SRD5A2 (0.72) | SRD5A2MAPTKDM4ELMNAPOLB | |
| SCHEMBL21243832 | 0.85 | SRD5A2 (0.72) | SRD5A2MAPTKDM4ELMNAPOLB | |
| SCHEMBL8490600 | 0.85 | PARP15 (0.54) | SRD5A2PARP15PARP10PARP2RAB9A | |
| SCHEMBL6654857 | 0.85 | FFAR1 (0.53) | SRD5A2PARP15PARP10PARP2RAB9A | |
| SCHEMBL8185095 | 0.84 | HTT (0.62) | LMNACTBP2FFAR1MMP2HTT | |
| SCHEMBL8410055 | 0.82 | OPRM1 (0.57) | SRD5A2MMP2 | |
| SCHEMBL11564197 | 0.82 | RAB9A (0.54) | PARP15PARP10PARP2RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040043904-A1 | N-(4-pyrazolyl) amide derivatives, chemicals for agricultural and horticultural use, and usage of the same | NIHON NOHYAKU CO., LTD. (JP) | 2004-03-04 | — | — | US | disclosed |
| EP-1319657-A1 | N-(4-PYRAZOLYL)AMIDE DERIVATIVES, CHEMICALS FOR AGRICULTURAL AND HORTICULTURAL USE, AND USAGE OF THE SAME | Nihon Nohyaku Co., Ltd. (JP) | 2003-06-18 | — | — | EP | disclosed |
| US-4168385-A | LOWERING OF STEROL AND TRIGLYCERIDE SERUM LEVELS | AMERICAN CYANAMID COMPANY (US) | 1979-09-18 | — | — | US | disclosed |
| US-4125729-A | Hypolipemic α-aryloxy para substituted phenyl acetic acid compounds | AMERICAN CYANAMID COMPANY (US) | 1978-11-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040043904-A1 | N-(4-pyrazolyl) amide derivatives, chemicals for agricultural and horticultural use, and usage of the same | CBR3, CYP8B1, CBR1 | SRD5A2 742/4885PARP15 4592/4885PARP10 4623/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.