Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 5/20 | 0.68 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.68 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.68 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11566398 | 0.87 | OPRM1 (0.67) | OPRM1OPRD1OPRK1SLC22A1ABCB1 | |
| SCHEMBL11563405 | 0.83 | OPRM1 (0.68) | OPRM1OPRD1OPRK1 | |
| SCHEMBL11566837 | 0.83 | OPRM1 (0.62) | OPRM1OPRD1OPRK1SLC22A1ABCB1 | |
| SCHEMBL3162283 | 0.83 | OPRM1 (0.80) | OPRM1OPRD1OPRK1SLC22A1ABCB1 | |
| SCHEMBL11567263 | 0.83 | OPRM1 (0.53) | OPRM1OPRD1OPRK1 | |
| SCHEMBL11565824 | 0.82 | OPRM1 (0.61) | OPRM1OPRD1OPRK1SLC22A1ABCB1 | |
| SCHEMBL10436786 | 0.82 | OPRM1 (0.65) | OPRM1OPRD1OPRK1SLC22A1ABCB1 | |
| SCHEMBL11518793 | 0.81 | OPRM1 (0.72) | OPRM1OPRD1OPRK1SLC22A1ABCB1 | |
| SCHEMBL11565181 | 0.81 | OPRM1 (1.00) | OPRM1OPRD1OPRK1SLC22A1ABCB1 | |
| Hydrochloric Acid SCHEMBL11455537 | 0.81 | OPRM1 (0.59) | OPRM1OPRD1OPRK1SLC22A1ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4179569-A | ANALGESIC INTERMEDIATES | JANSSEN PHARMACEUTICA N.V. (BE) | 1979-12-18 | — | — | US | disclosed |
| US-3998834-A | ANALGESICS | JANSSEN PHARMACEUTICA N.V. (BE) | 1976-12-21 | — | — | US | disclosed |