Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 16/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.53 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11563405 | 0.89 | OPRM1 (0.68) | OPRM1OPRD1OPRK1CACNA1C | |
| SCHEMBL11564147 | 0.83 | OPRM1 (0.68) | OPRM1OPRD1OPRK1 | |
| SCHEMBL6045452 | 0.81 | OPRM1 (0.62) | OPRM1OPRD1OPRK1CACNA1C | |
| SCHEMBL3303683 | 0.79 | OPRM1 (0.80) | OPRM1OPRD1OPRK1CACNA1C | |
| SCHEMBL11567961 | 0.79 | OPRM1 (0.55) | OPRM1OPRD1OPRK1CACNA1C | |
| SCHEMBL4236765 | 0.77 | OPRM1 (0.63) | OPRM1OPRD1OPRK1CACNA1C | |
| SCHEMBL20953915 | 0.76 | CACNA1C (0.68) | OPRM1OPRD1OPRK1CACNA1C | |
| SCHEMBL11565239 | 0.76 | OPRM1 (0.68) | OPRM1OPRD1OPRK1CACNA1C | |
| SCHEMBL8636898 | 0.75 | OPRM1 (0.50) | OPRM1OPRD1OPRK1CACNA1C | |
| SCHEMBL4252412 | 0.75 | OPRM1 (0.58) | OPRM1OPRD1OPRK1CACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4179569-A | ANALGESIC INTERMEDIATES | JANSSEN PHARMACEUTICA N.V. (BE) | 1979-12-18 | — | — | US | disclosed |
| US-3998834-A | ANALGESICS | JANSSEN PHARMACEUTICA N.V. (BE) | 1976-12-21 | — | — | US | disclosed |