Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1E | P28566 | 3/20 | 0.54 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.50 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28373611 | 0.92 | HTR1E (0.65) | HTR1ES1PR3LMNAMEN1KMT2A | |
| SCHEMBL193456 | 0.90 | HTR1E (0.63) | HTR1ES1PR3LMNAMEN1KMT2A | |
| SCHEMBL66920 | 0.87 | LMNA (0.54) | HTR1ES1PR3LMNAMEN1KMT2A | |
| SCHEMBL11359972 | 0.85 | HTR1E (0.53) | HTR1ES1PR3LMNAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11359974 | 0.85 | LMNA (0.53) | HTR1ES1PR3LMNAMEN1KMT2A | |
| SCHEMBL22188704 | 0.83 | HTR1E (0.51) | HTR1ES1PR3LMNAMEN1KMT2A | |
| SCHEMBL4176732 | 0.83 | HTR1E (0.51) | HTR1ES1PR3LMNAMEN1KMT2A | |
| SCHEMBL10298827 | 0.81 | LMNA (0.58) | HTR1ES1PR3LMNAMEN1KMT2A | |
| SCHEMBL17078315 | 0.80 | LMNA (0.49) | HTR1ES1PR3LMNAMEN1KMT2A | |
| SCHEMBL69127 | 0.79 | HTR1E (0.65) | HTR1ES1PR3LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119118807-A | Method for synthesizing aryl butanone by ligand-regulated nickel-catalyzed aryl cyclopropyl ketone ring-opening hydrogenation | 陕西师范大学 | 2024-12-13 | — | — | CN | disclosed |
| EP-2242736-B1 | PROCESS FOR THE PREPARATION OF PHARMACEUTICAL INTERMEDIATES | EGIS GYOGYSZERGYAR NYILVANOSAN MUEKOEDOE RESZVENYTARSASAG (HU) | 2011-09-14 | — | — | EP | disclosed |
| US-20110040093-A1 | PROCESS FOR THE PREPARATION OF PHARMACEUTICAL INTERMEDIATE | EGIS GYOGYSZERGYAR NYILVANOSAN MUKODO RESZVENYTARSASAG (HU) | 2011-02-17 | — | — | US | disclosed |
| EP-2242736-A1 | PROCESS FOR THE PREPARATION OF PHARMACEUTICAL I NTERM EDIATES | Egis Gyógyszergyár Nyilvánosan Müködö Részvénytársaság (HU) | 2010-10-27 | — | — | EP | disclosed |
| WO-2009068924-A1 | PROCESS FOR THE PREPARATION OF PHARMACEUTICAL I NTERM EDIATES | EGIS GYÓGYSZERGYÁR NYILVÁNOSAN MÜKÖDÖ (HU) | 2009-06-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110040093-A1 | PROCESS FOR THE PREPARATION OF PHARMACEUTICAL INTERMEDIATE | CYP2F1, CYP4F3, CYP4F11 | HTR1E 3664/4885S1PR3 1919/4885LMNA 4136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.