Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | HTR1E | P28566 | 3/20 | 0.54 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.50 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | SRC | P12931 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11359974 | 0.98 | LMNA (0.53) | LMNAHTR1ES1PR3MEN1KMT2A | |
| SCHEMBL67619 | 0.92 | HTR1E (0.60) | LMNAHTR1ES1PR3MEN1KMT2A | |
| SCHEMBL28622389 | 0.92 | HTR1E (0.65) | LMNAHTR1ES1PR3MEN1KMT2A | |
| SCHEMBL69127 | 0.92 | HTR1E (0.65) | LMNAHTR1ES1PR3MEN1KMT2A | |
| SCHEMBL67219 | 0.90 | HTR1E (0.63) | LMNAHTR1ES1PR3MEN1KMT2A | |
| SCHEMBL12531975 | 0.90 | HTR1E (0.63) | LMNAHTR1ES1PR3MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11526873 | 0.88 | HTR1E (0.61) | LMNAHTR1ES1PR3MEN1KMT2A | |
| SCHEMBL1156417 | 0.87 | HTR1E (0.54) | LMNAHTR1ES1PR3MEN1KMT2A | |
| SCHEMBL31066516 | 0.87 | HTR1E (0.47) | LMNAHTR1ES1PR3MEN1KMT2A | |
| SCHEMBL13114874 | 0.87 | CACNA2D1 (0.50) | LMNAHTR1ES1PR3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4618615-A | INSECTICIDES, MITICIDES | CIBA-GEIGY CORPORATION (US) | 1986-10-21 | — | — | US | claimed |
| EP-0109934-A1 | Alpha-cyclopropyl-alpha-phenyl acetates and their salts, processes for their preparation and their use as pesticides | CIBA-GEIGY AG (CH) | 1984-05-30 | — | — | EP | claimed |
| US-4377593-A | α-Isopropyl- and α-cyclopropylphenylacetates and use thereof in pest control | CIBA-GEIGY CORPORATION (US) | 1983-03-22 | — | — | US | claimed |
| EP-0059685-A1 | Alpha-isopropyl or alpha-cyclopropylphenyl acetates, process for their preparation and their use in pest control | CIBA-GEIGY AG (CH) | 1982-09-08 | — | — | EP | claimed |
| EP-0008334-B1 | ALPHA-PHENYL-ALPHA-CYCLOPROPANE-ACETIC ACID ESTERS, THEIR PREPARATION AND USE AS PESTICIDES | CIBA-GEIGY AG (CH) | 1981-10-14 | — | — | EP | claimed |
| EP-0009637-A1 | Alpha-phenyl-alpha-isopropyl acetates, process for their preparation, pesticides containing them and the use of these acetates in the control of pests | CIBA-GEIGY AG (CH) | 1980-04-16 | — | — | EP | claimed |
| EP-0008334-A1 | Alpha-phenyl-alpha-cyclopropane-acetic acid esters, their preparation and use as pesticides | CIBA-GEIGY AG (CH) | 1980-03-05 | — | — | EP | claimed |
| EP-0006630-A1 | Alpha-phenyl-alpha-cyclopropane acetic acid esters, process for their preparation and their use as insecticides | CIBA-GEIGY AG (CH) | 1980-01-09 | — | — | EP | claimed |
| US-12534451-B2 | Small molecule modulators of PanK | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. (US) | 2026-01-27 | — | — | US | disclosed |
| CN-113372319-B | Amine group-containing delta-lactone compound and preparation method thereof | 东北师范大学 | 2023-09-05 | — | — | CN | disclosed |
| US-20220185796-A1 | SMALL MOLECULE MODULATORS OF PANK | ST. JUDE CHILDREN'S RESEARCH HOSPITAL | 2022-06-16 | — | — | US | disclosed |
| EP-3946312-A2 | SMALL MOLECULE MODULATORS OF PANK | St. Jude Children's Research Hospital (US) | 2022-02-09 | — | — | EP | disclosed |
| CN-113372319-A | Delta-lactone compound containing amino and preparation method thereof | 东北师范大学 | 2021-09-10 | — | — | CN | disclosed |
| WO-2020198526-A2 | SMALL MOLECULE MODULATORS OF PANK | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2020-10-01 | — | — | WO | disclosed |
| EP-0006630-A1 | Alpha-phenyl-alpha-cyclopropane acetic acid esters, process for their preparation and their use as insecticides | CIBA-GEIGY AG (CH) | 1980-01-09 | — | — | EP | disclosed |
| EP-0006630-A1 | Alpha-phenyl-alpha-cyclopropane acetic acid esters, process for their preparation and their use as insecticides | CIBA-GEIGY AG (CH) | 1980-01-09 | — | — | EP | disclosed |
| US-4163788-A | ANTIINFLAMMATORY | CIBA-GEIGY CORPORATION (US) | 1979-08-07 | — | — | US | disclosed |
| US-4137324-A | Optionally substituted phenyl-α-cyclopropyl acetic acid esters and use as insecticides | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1979-01-30 | — | — | US | disclosed |
| US-4126691-A | ANTIINFLAMMATORY | CIBA-GEIGY CORPORATION (US) | 1978-11-21 | — | — | US | disclosed |
| US-3997669-A | ANTIINFLAMMATORY | CIBA-GEIGY CORPORATION (US) | 1976-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12534451-B2 | Small molecule modulators of PanK | PANK2, PANK1, PANK3 | LMNA 2257/4885HTR1E 4574/4885S1PR3 3745/4885 |
| US-20220185796-A1 | SMALL MOLECULE MODULATORS OF PANK | PANK2, PANK1, PANK3 | LMNA 2078/4885HTR1E 4389/4885S1PR3 2506/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.