Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isophthalic Acid SCHEMBL692542 | 0.85 | KMO (0.43) | KMOPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL460145 | 0.82 | MAPT (0.33) | ALDH1A1HPGDMEN1KMT2AMAPT | |
| Isophthalic Acid SCHEMBL472832 | 0.81 | KMO (0.47) | KMOALDH1A1HPGDKDM4EMEN1 | |
| Isophthalic Acid SCHEMBL2133440 | 0.80 | KMO (0.46) | KMOALDH1A1HPGDKDM4EMEN1 | |
| Isophthalic Acid SCHEMBL374460 | 0.80 | KMO (0.46) | KMOALDH1A1HPGDKDM4EMEN1 | |
| Isophthalic Acid SCHEMBL170729 | 0.79 | KMO (0.48) | KMOALDH1A1HPGDKDM4EMEN1 | |
| Isophthalic Acid SCHEMBL1401144 | 0.79 | ALDH1A1 (0.50) | KMOALDH1A1HPGDGAAHSD17B10 | |
| Isophthalic Acid SCHEMBL9282767 | 0.79 | KMO (0.50) | KMOPDE4APDE4BPDE4CPDE4D | |
| Ethylene Glycol SCHEMBL487137 | 0.78 | MEN1 (0.31) | ALDH1A1MEN1KMT2AEPHX1 | |
| Isophthalic Acid SCHEMBL8500503 | 0.75 | KMO (0.49) | KMOMEN1KMT2ACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4172075-A | Fluoro-steroids and processes for their manufacture | CIBA-GEIGY CORPORATION (US) | 1979-10-23 | — | — | US | disclosed |
| US-3981237-A | Plastic rotary printing screens construction method therefor | RHODES JOHN M | 1976-09-21 | — | — | US | disclosed |