Isophthalic Acid

Isophthalic Acid

SCHEMBL2133440

O=C(O)c1cccc(C(=O)O)c1.O=C1OCCCCCCOC(=O)c2ccc1cc2

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMO O15229 3/20 0.46
CA1 P00915 2/20 0.44
CA2 P00918 2/20 0.44
CA9 Q16790 2/20 0.44
CA12 O43570 1/20 0.44
CA6 P23280 1/20 0.44
HPGD P15428 3/20 0.44
ALDH1A1 P00352 2/20 0.44
HSD17B10 Q99714 2/20 0.44
KDM4E B2RXH2 1/20 0.44
MEN1 O00255 1/20 0.44
GAA P10253 1/20 0.44
KMT2A Q03164 1/20 0.44
CYP2C9 P11712 3/20 0.43
CYP2D6 P10635 2/20 0.43
CYP1A2 P05177 2/20 0.43
HIF1A Q16665 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2C19 P33261 1/20 0.43
KEAP1 Q14145 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isophthalic Acid SCHEMBL472832 0.98 KMO (0.47) KMOCA1CA2CA9CA12
Isophthalic Acid SCHEMBL374460 0.97 KMO (0.46) KMOCA1CA2CA9CA12
Isophthalic Acid SCHEMBL170729 0.93 KMO (0.48) KMOCA1CA2CA9CA12
Isophthalic Acid SCHEMBL1324997 0.91 ALDH1A1 (0.44) KMOCA1CA2CA9CA12
Isophthalic Acid SCHEMBL11371041 0.89 KMO (0.40) KMOCA1CA2CA9CA12
Isophthalic Acid SCHEMBL8500503 0.88 KMO (0.49) KMOCA1CA2CA9CA12
Isophthalic Acid SCHEMBL1325894 0.88 HDAC3 (0.41) KMOCA1CA2CA9CA12
Terephthalic Acid SCHEMBL8151569 0.88 RARB (0.44) KMOCA1CA2CA9HPGD
Terephthalic Acid SCHEMBL1234263 0.87 TSHR (0.46) ALDH1A1RXRARXRBNPC1RAB9A
Sebacic Acid SCHEMBL1326195 0.87 HDAC3 (0.44) KMOALDH1A1MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4041206-A POLY-ETHYLENE TEREPHTHALATE, -BUTYLENE TEREPHTHALATE, AND COPOLYMERS, PHOTOGRAPHIC FILMS, ELECTRICAL INSULATION TORAY INDUSTRIES, INC. (JA) 1977-08-09 US claimed
US-4010221-A COPOLYESTER COMPOSITIONSBLENDS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1977-03-01 US claimed
EP-2915759-B1 RESIN COATED METAL PLATE FOR DRAWN AND IRONED CAN, DRAWN AND IRONED CAN, AND DRAWN AND IRONED CAN MANUFACTURING METHOD TOYO KOHAN CO LTD (JP) 2019-10-09 EP disclosed
EP-2554277-B1 RESIN-COATED AL PLATE FOR DRAWN AND IRONED CAN WITH EXCELLENT LUSTER AND METHOD FOR PRODUCING DRAWN AND IRONED CAN TOYO KOHAN CO LTD (JP) 2019-06-19 EP disclosed
US-10086586-B2 Composite Al material for drawn and ironed can TOYO KOHAN CO., LTD. (JP) 2018-10-02 US disclosed
US-9662699-B2 Resin-coated A1 plate for drawn and ironed can with excellent luster and method for producing drawn and ironed can TOYO KOHAN CO., LTD. (JP) 2017-05-30 US disclosed
EP-3157408-A2 DEVICES AND METHODS TO PROVIDE HANDS FREE SCLERAL DEPRESSION DURING OPHTHALMIC PROCEDURES Ganiban, Gary (US) 2017-04-26 EP disclosed
US-20170105873-A1 MINIMALLY INVASIVE APPARATUS AND METHOD FOR TREATING THE RETINA MAZZOCCHI RUDY A (US) 2017-04-20 US disclosed
US-9532902-B2 Minimally-invasive method and apparatus for restructuring the retina Optistent, Inc. (US) 2017-01-03 US disclosed
WO-2015195748-A2 DEVICES AND METHODS TO PROVIDE HANDS FREE SCLERAL DEPRESSION DURING OPHTHALMIC PROCEDURES GANIBAN GARY (US) 2015-12-23 WO disclosed
US-20150359529-A1 DEVICES AND METHODS TO PROVIDE HANDS FREE SCLERAL DEPRESSION DURING OPHTHALMIC PROCEDURES ALCON INC. (CH) 2015-12-17 US disclosed
EP-0168805-A2 Novel multi-layer articles NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1986-01-22 EP disclosed
EP-0059635-B1 EASILY OPENABLE VESSEL CLOSURE AND PROCESS FOR PREPARATION THEREOF TOYO SEIKAN KAISHA LIMITED (JP) 1985-06-05 EP disclosed
US-4428494-A Easily-openable heat seal lid TOYO SEIKAN KAISHA, LTD. (JP) 1984-01-31 US disclosed
US-4397401-A Easily openable vessel closure and process for preparation thereof TOYO SEIKAN KAISHA LTD. (JP) 1983-08-09 US disclosed
EP-0078625-A1 Easily-openable heat seal lid TOYO SEIKAN KAISHA LIMITED (JP) 1983-05-11 EP disclosed
EP-0059635-A2 Easily openable vessel closure and process for preparation thereof TOYO SEIKAN KAISHA LIMITED (JP) 1982-09-08 EP disclosed
US-4143790-A POLYESTER COATING TORAY INDUSTRIES, INC. (JP) 1979-03-13 US disclosed
US-4041206-A POLY-ETHYLENE TEREPHTHALATE, -BUTYLENE TEREPHTHALATE, AND COPOLYMERS, PHOTOGRAPHIC FILMS, ELECTRICAL INSULATION TORAY INDUSTRIES, INC. (JA) 1977-08-09 US disclosed
US-4010221-A COPOLYESTER COMPOSITIONSBLENDS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1977-03-01 US disclosed